cgi-bin/community/feature/200406.pl

   1 use strict;
   2 use CXGN::Page;
   3 my $page=CXGN::Page->new('200406.html','html2pl converter');
   4 $page->header('The Van Der Knaap Lab');
   5 print<<END_HEREDOC;
   6
   7   <center>
   8     <h1>The van der Knaap lab</h1>
   9
  10     <p class="footnote"><img src="/static_content/community/feature/200406-1.jpg" width="720" height=
  11     "540" border="0" alt="Members of the van der Knaap lab" /> From
  12     Left: Marin Brewer, Amy Barrett, Maria Stillitano, Nic Welty,
  13     Erin Schaffner, Jenny Moyseenko; Esther van der Knaap, Jason
  14     Dickey, and Han Xiao</p>
  15   </center>
  16
  17   <p><img src="/static_content/community/feature/200406-3.jpg" width="377" height="300" border="0"
  18   align="right" hspace="15" vspace="10" alt="rectangle fruit" />
  19   Breeding and mutation analysis in tomato have resulted in a
  20   diverse germplasm collection, providing a rich resource for
  21   studies on fruit morphology. Fruit morphological changes often
  22   occur during ovary development prior to pollination or during
  23   maturation of the fruit after pollination and fertilization.
  24   Therefore, tomato varieties displaying altered fruit shape
  25   provide unique insights into developmental processes controlling
  26   ovary and fruit growth and maturation. Understanding the
  27   molecular genetic basis of diversity in fruit form will allow
  28   insights into evolutionary processes in tomato as well as other
  29   fruit-bearing crops, and modification of developmental processes
  30   regulating ovary and fruit formation.</p>
  31
  32   <p>In our laboratory, the basis of variation in tomato fruit
  33   shape is studied by taking on a multi-tiered approach. Firstly,
  34   we are performing a <span style="color:red">genetic</span>
  35   analysis to identify loci that control variation in fruit shape
  36   (<a href=
  37   "http://www.oardc.ohio-state.edu/vanderknaap/documents/longjohn.pdf">van
  38   der Knaap et al., 2002</a>; <a href=
  39   "http://www.oardc.ohio-state.edu/vanderknaap/documents/stufferms.pdf">
  40   van der Knaap and Tanksley 2003</a>). Selected loci will be
  41   fine-mapped to allow identification of the genes underlying the
  42   trait (<a href=
  43   "http://www.oardc.ohio-state.edu/vanderknaap/documents/sun.pdf">van
  44   der Knaap and Tanksley, 2001</a>; van der Knaap et al, manuscript
  45   in preparation). Secondly, we are conducting <span style=
  46   "color:red">developmental</span> analyses to describe when
  47   changes in fruit shape occur during ovary and/or fruit growth. In
  48   addition, we want to know which tissues(s) in the ovary or fruit
  49   display altered growth characteristics to allow changes in final
  50   fruit shape. Thirdly, we are taking a <span style=
  51   "color:red">molecular</span> approach to identify genes with
  52   altered expression levels during ovary and fruit growth. Also, we
  53   are identifying genes with different levels of expression due to
  54   allelic variation at fruit shape loci. This information will
  55   allow insights into networks of genes and biochemical processes
  56   potentially downstream from fruit shape loci, and how fruit
  57   morphology is regulated. Lastly, we are taking a <span style=
  58   "color:red">bioinformatic</span> approach by developing software
  59   to semi-automatically quantify fruit morphological
  60   characteristics and integrating analysis of these shape
  61   characteristics with gene expression and genotype
  62   information.</p>
  63
  64   <p><img src="/static_content/community/feature/200406-2.jpg" width="720" height="486" border="0"
  65   alt="circle fruit" /></p>
  66
  67   <h2>Contact Information</h2>
  68
  69   <p>Esther van der Knaap<br />
  70   Department of Horticulture and Crop Science<br />
  71   204A Williams Hall, The Ohio State University/OARDC<br />
  72   Wooster OH 44691<br />
  73   Tel:330-263-3822; FAX:330-263-3887; email: <a href=
  74   "mailto:vanderknaap.l\@osu.edu">vanderknaap.1\@osu.edu</a><br />
  75   <a href=
  76   "http://www.oardc.ohio-state.edu/vanderknaap/">http://www.oardc.ohio-state.edu/vanderknaap</a><br />
  77   </p>
  78 END_HEREDOC
  79 $page->footer();