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116 <div class="style1" align="right">Case-deletion Diagnostics (<span
117 style="font-family: monospace;">cdd</span>)<br>
118 </div>
119 </div>
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123 <h3 class="heading1">Synopsis</h3>
124 <tt>$ cdd [ -h | -? ] [ --help ]<br>
125 --case_column='column_name|column_number'<br>
126 [ --bins=integer ]<br>
127 [ --selection_method=''random'|'consecutive'' ]<br>
128 [ --abort_on_fail ]<br>
129 [ --clean ]<br>
130 [ --compress ]<br>
131 [ --cpu_time=integer ]<br>
132 [ --debug=0 ]<br>
133 [ --debug_package='string' ]<br>
134 [ --debug_subroutine='string' ]<br>
135 [ --directory='string' ]<br>
136 [ --extra_data_file='string' ]<br>
137 [ --extra_files='string' ]<br>
138 [ --grid_batch_size=integer ]<br>
139 [ --missing_data_token='string' ]<br>
140 [ --nm_directory='string' ]<br>
141 [ --nm_version='string' ]<br>
142 [ --outputfile='string' ]<br>
143 [ --picky ]<br>
144 [ --remove_temp_files ]<br>
145 [ --results_file='string' ]<br>
146 [ --retries=integer ]<br>
147 [ --run_on_nordugrid ]<br>
148 [ --seed='string' ]<br>
149 [ --threads=integer ]<br>
150 [ --tweak_inits ]</tt>
151 <h3 class="heading1">Description</h3>
152 <p> The Case-deletion Diagnostics tool is run from the command line
153 with a few mandatory arguments. It is run as a diagnostic after
154 a model is regarded finished or at least mature enough for validation. You need to specify the NONMEM model file
155 with a model that has successful termination. You also have to
156 specify the number or the name of the column in the data file, on which to
157 select for deletion. This is done with the case_column option.</p>
158 <h3 class="heading1">Options</h3>
160 The options are given here in their long form. Any option may be
161 abbreviated to any nonconflicting prefix. The <span class="style2">-threads</span> option
162 may be abbreviated to <span class="style2">-t </span>(or even <span class="style2">-thr</span>) but <span class="style2">-debug</span> may not be
163 abbreviated to -d because it conflicts with <span class="style2">-debug_packages</span> and<span class="style2">-debug_subroutines</span>.</p>
164 <p> The following options are valid:</p>
165 <p class="style2"> -h | -?</p>
166 <p> With -h or -? cdd will print a list of options and then exit.</p>
167 <p class="style2"> -help</p>
168 <p> With -help cdd will print a longer help message.</p>
169 <p class="style2"> -bins=number</p>
170 <p> Sets the number of data bins or cdd data sets that should be used. If the
171 number of unique values or factors in the based_on column is
172 higher than the number of bins, one or more factors will be
173 deleted in each of the cdd data set. Specifying bins as higher than
174 the number of factors will have no effect. In that case the bin number will be
175 set to the number of factors.
176 The default value is equal to the number of unique values in the based_on column.</p>
177 <p class="style2"> -selection_method='random' or 'consecutive'</p>
178 <p> Specifies whether the factors selected for exclusion should be
179 drawn randomly or consecutively from the data file.
180 Default value = 'consecutive'</p>
181 <p class="style2"> -case_column=column_name|column_number</p>
182 <p> See the <a href="execute_docs.php">execute documentation</a> for a description of common options.</p>
183 <h3 class="heading1">Output</h3>
184 <p>The Case-deletion Diagnostics tool creates a log file and a result file. Both are by default placed in the cdd_dirX directory and are called cdd.csv and cdd-results.csv. </p>
185 <p class="heading1">Example</p>
186 <p class="style2">
187 cdd modelfile.mod -case_column=10
188 </p>
190 This will perform a Case-deletion Diagnostic based on the factors in column number ten. If,
191 for example, that column holds the names of the seven centers
192 included in the study, this command will create seven copies of
193 the data set, each with individuals from one specific
194 center deleted. Say that the centers are numbered 1 to 7. Then
195 all individuals from center 1 will be excluded from data set 1, the individuals from center 2 will be excluded from data set 2, and so on.
196 </p>
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