1 ; This is the PsN configuration file. PsN will look for this file
2 ; (psn.conf) at two different positions, in PsN installation directory
3 ; and in either the user's home-directory (UNIX) or the user's desktop
4 ; (Miscrosoft Windows). If a user-level configuration file is found,
5 ; the settings in this file will override the settings in the
6 ; system-wide configuration file. This is important to remember when
7 ; trying to sort out a PsN-related problem.
9 ; Available output styles are SPLUS, MATLAB and EXCEL
10 ; The only differences are:
12 ; missning_data 'NA' 'NaN' ''
13 ; Header row yes no yes
15 ; The default output style is EXCEL
18 ; Path to R (if installed). This is a new feature in PsN 2.2.2 and
19 ; enables automatic calculation of conditional weighted residuals
20 ; (CWRES). This feature requires that Xpose version 4.0 preview
21 ; release 5 is also installed.
24 ; Path to perl. This default to "C:\Perl\bin\perl.exe" on windows and
25 ; simply 'perl' on unix.
26 ; perl = c:\Perl\bin\perl.exe
28 ; These two lines should not be modified, they are used to disable
29 ; experimental features of PsN.
32 ; Further experimental features
33 ;database_server=localhost
37 ; Set the job polling interval to a value that is suitable to your
38 ; system. The general rule is that the larger the distributed system
39 ; gets, the longer the polling interval needs to be. Slow systems,
40 ; i.e. small amount of RAM, low bandwidth network or slow filesystem
41 ; need longer intervals. Single machine systems can use the default
42 ; polling interval of one second.
43 job_polling_interval=1
45 ; If you have an openMosix cluster system with varying number of
46 ; available nodes, you may want to use the adaptive parallel processes
47 ; feature of PsN. You will need a service running that keeps track of
48 ; the available resources and the requested number of parallel
49 ; jobs. Please contact the PsN development team to get a copy of our
50 ; service tool called moshog.
52 ; Requests to the moshog service can be made after each job poll or
54 polls_per_moshog_request=5
56 ; The following lines are LSF options.
57 ;remote_perl=some_path_to_a_perl_binary_working_on_remote_hosts
59 ; The follwing lines are UD options.
62 ; The following lines are nordugrid options
63 ; ng_clusters=some_path_to_a_file_with_cluster_names
66 zink_dir="/home/pontus/"
68 ; The lines below are examples of how you can specify different
69 ; installations of NONMEM. By default, PsN will use the NONMEM
70 ; installation identified by the name 'default'. If only one
71 ; installation is specified, this will be used by default even if it
72 ; isn't called 'default'. To use other installations with the
73 ; PsN-utilities scripts, use the "-nm_version" command line
74 ; option. The last line is an example of how a windows installation
75 ; could be configured (notice the use of a backslash(\) instead of a
79 default=/export/home/nmvi1.0,6
83 ; The compiler section specifies the name and compiler flags of the
84 ; compiler executable. It is also possible to include a path. Like
86 ; name=c:\fortran\fl32
89 ; Gnu fortran compiler
94 ; Intel Fortran compiler
99 ;;MS Fortran Powerstation
104 ;;Digitial Visual Fortran 5.0
106 ;options=/optimize:4 /fltconsistency /fpe:3
107 ;options=/optimize:1 /fpe:0
110 ; Options valid for all tools
113 [default_execute_options]
114 ; Options valid for execute
116 ; All correlations above this number will be listed
117 correlation_limit=0.9
119 ; An error will be rised if the condition number is greater than this
122 condition_number_limit = 1000
124 ; If a parameter estimate is equal to a bound with this many
125 ; significant digits, a warning will be printed.
127 near_bound_sign_digits = 2
129 ; When the bound is zero, the check above is not valid. Use this limit
132 near_zero_boundary_limit = 0.001
134 ; The off-diagonal elements are checked against +-1 with this many
135 ; significant digits.
137 sign_digits_off_diagonals = 2
139 ; Coefficients of variation larger than these numbers will produce
142 large_theta_cv_limit = 0.30
143 large_omega_cv_limit = 0.50
144 large_sigma_cv_limit = 0.30
146 ; Confidence level for confidence intervals (percentage value)
148 confidence_level = 95
150 ; Precision in -summarize output.
154 [default_llp_options]
155 ; Options valid for llp
157 ; Check if the confidence intervals include this value
158 within_interval_check = 0
160 ; Check if the CI limit distance ratio is above this value or below its reciprocal value
161 theta_interval_ratio_check = 1.3
162 omega_interval_ratio_check = 1.6
163 sigma_interval_ratio_check = 1.6
165 [default_cdd_options]
166 ; Options valid for cdd
168 ; Mark the cook-scores and covariance-ratios that lie outside this number of standard deviations
169 outside_n_sd_check = 2
171 [default_bootstrap_options]
172 ; Options valid for the bootstrap
174 ; Use these rules for calculating the bootstrap results
175 skip_minimization_terminated = 1
176 skip_covariance_step_terminated = 0
177 skip_with_covstep_warnings = 0
178 skip_estimate_near_boundary = 1
180 ; Warn if the ratio of successful minimizations/total runs is lower than this value
181 minimization_successful_limit = 0.8
183 ; Warn if the ratio of successful covariance steps/total runs is lower than this value
184 covariance_step_successful_limit = 0.8
186 ; Warn if the ratio of runs with covariance step warnings/total runs is higher than this value
187 covariance_step_warnings_limit = 0.2
189 ; Warn if the ratio of runs with near boundary warnings/total runs is higher than this value
190 estimate_near_boundary_limit = 0.2
192 ; Warn if the ratio of runs with near boundary warnings/total runs is higher than this value
193 estimate_near_boundary_limit = 0.2
195 ; Use this level of confidence for the confidence intervals checks based on bootstrap standerd errors (%)
196 se_confidence_intervals_level = 5
198 ; Use this level of confidence for the confidence intervals checks based on bootstrap percentiles (%)
199 percentile_confidence_intervals_level = 5
201 ; Use this level of confidence for the confidence intervals checks based on bootstrap BCa percentiles (%)
202 bca_confidence_intervals_level = 5
204 ; Check if the confidence intervals based on bootstrap standerd errors include this value
205 se_confidence_intervals_check = 0
207 ; Check if the confidence intervals based on bootstrap percentiles include this value
208 percentile_confidence_intervals_check = 0
210 ; Check if the confidence intervals based on bootstrap BCa percentiles include this value
211 bca_confidence_intervals_check = 0
213 ; Warn if the absolute relative bias is larger than this value
214 large_bias_limit = 0.05