1 LOCUS KIF3C 4913 bp mRNA linear PRI 06-APR-2003
2 DEFINITION Homo sapiens kinesin family member 3C (KIF3C), mRNA.
4 VERSION NM_002254.2 GI:19923139
6 SOURCE Homo sapiens (human)
8 Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
9 Mammalia; Eutheria; Primates; Catarrhini; Hominidae; Homo.
10 REFERENCE 1 (bases 1 to 4913)
11 AUTHORS Sardella,M., Navone,F., Rocchi,M., Rubartelli,A., Viggiano,L.,
12 Vignali,G., Consalez,G.G., Sitia,R. and Cabibbo,A.
13 TITLE KIF3C, a novel member of the kinesin superfamily: sequence,
14 expression, and mapping to human chromosome 2 at 2p23
15 JOURNAL Genomics 47 (3), 405-408 (1998)
18 REFERENCE 2 (bases 1 to 4913)
19 AUTHORS Telford,E.A., Wightman,P., Leek,J., Markham,A.F., Lench,N.J. and
21 TITLE cDNA cloning, genomic organization, and chromosomal localization of
22 a novel human gene that encodes a kinesin-related protein highly
23 similar to mouse Kif3C
24 JOURNAL Biochem. Biophys. Res. Commun. 242 (2), 407-412 (1998)
27 REFERENCE 3 (bases 1 to 4913)
28 AUTHORS Telford,E.A.R., Wightman,P., Leek,J., Lench,N.J., Markham,A.F. and
30 TITLE Homo sapiens kinesin family member 3C (KIF3C), mRNA
31 JOURNAL Unpublished (1997)
32 COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final
33 NCBI review. The reference sequence was derived from AF035621.1.
34 On Apr 4, 2002 this sequence version replaced gi:4504868.
35 FEATURES Location/Qualifiers
37 /organism="Homo sapiens"
44 /db_xref="LocusID:3797"
49 /product="kinesin family member 3C"
50 /protein_id="NP_002245.2"
51 /db_xref="GI:19923140"
52 /db_xref="LocusID:3797"
54 /translation="MASKTKASEALKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTL
55 RNPRAAPGELPKTFTFDAVYDASSKQADLYDETVRPLIDSVLQGFNGTVFAYGQTGTG
56 KTYTMQGTWVEPELRGVIPNAFEHIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKE
57 PGKRLELKENPETGVYIKDLSSFVTKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHA
58 IFIITVECSERGSDGQDHIRVGKLNLVDLAGSERQNKAGPNTAGGAATPSSGGGGGGG
59 GSGGGAGGERPKEASKINLSLSALGNVIAALAGNRSTHIPYRDSKLTRLLQDSLGGNA
60 KTIMVATLGPASHSYDESLSTLRFANRAKNIKNKPRVNEDPKDTLLREFQEEIARLKA
61 QLEKRGMLGKRPRRKSSRRKKAVSAPPGYPEGPVIEAWVAEEEDDNNNNHRPPQPILE
62 SALEKNMENYLQEQKERLEEEKAAIQDDRSLVSEEKQKLLEEKEKMLEDLRREQQATE
63 LLAAKYKAMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRREREMQQEMMLRDEE
64 TMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHDEYIRVRQDLEEAQNEQT
65 RELKLKYLIIENFIPPEEKNKIMNRLFLDCEEEQWKFQPLVPAGVSSSQMKKRPTSAV
66 GYKRPISQYARVAMAMGSHPRYRAENIMFLELDVSPPAVFEMEFSHDQEQDPRALHME
67 RLMRLDSFLERPSTSKVRKSRSWCQSPQRPPPSTTHASLASASLRPATVADHE"
68 misc_feature 199..1251
70 /note="kinesin; Region: Kinesin motor domain"
71 /db_xref="CDD:pfam00225"
74 /note="encodes ATP/GTP-binding site motif"
77 /note="encodes kinesin motor domain signature"
78 polyA_signal 4889..4894
80 BASE COUNT 1150 a 1342 c 1355 g 1066 t
82 1 cctcccagcg tccccaccct aggaggctgc atgcggattg aagacgtgcg cctgggggct
83 61 gggccggccc cgctgatccc gacctagcga gcaggatagc aggaccgccc aggctgcgga
84 121 ggggctcggg ggcaggaagg tcagagcagc aagatggcca gtaagaccaa ggccagcgag
85 181 gccctcaagg tggtggcccg gtgccgcccc ctcagcagga aggaggaggc tgctggtcac
86 241 gagcagatcc tgaccatgga cgtgaaactg ggccaggtga ccctgcggaa cccccgcgcc
87 301 gccccggggg agctgcccaa gaccttcacc tttgacgccg tgtatgatgc cagctccaag
88 361 caggccgacc tgtatgacga aaccgtgagg cccctgatag actccgtgct ccagggtttc
89 421 aatggcacgg tgtttgccta tggccagacg ggcactggca agacctatac catgcagggg
90 481 acctgggtgg agcccgagct gcgcggggtc atcccgaatg cctttgagca catcttcacc
91 541 cacatctccc gctcccagaa ccaacagtac ctggtccggg cctcctattt ggagatctac
92 601 caggaagaga ttcgagacct gctctccaag gagccgggca agaggctaga gctgaaagag
93 661 aaccccgaga ctggcgtcta catcaaggac ctctcctcct tcgtcaccaa gaatgtcaag
94 721 gagattgagc atgtgatgaa cctggggaac cagacccggg ctgtgggcag cacccacatg
95 781 aatgaggtca gctcccgctc ccatgccatc ttcatcatca ctgtggagtg cagcgaacgt
96 841 ggctctgatg gccaggacca catccgagtg ggcaagctca acctcgtgga cctggctggc
97 901 agcgagaggc agaacaaggc aggccccaac acagcgggag gggcagccac accatcctcg
98 961 ggtggcggtg gtggcggtgg aggcagtggt ggtggtgctg gtggagagag gcctaaggaa
99 1021 gcctccaaaa tcaacctctc attatctgcc ctgggcaacg tgattgctgc cctggcgggc
100 1081 aacaggagca cccacattcc ctaccgggac tccaagctga cccggctgct ccaggactcc
101 1141 ctggggggga atgcgaagac catcatggta gccacactgg ggccagcttc tcacagctac
102 1201 gatgagagcc tctccacctt gcgctttgcc aaccgagcca agaacatcaa gaacaagccc
103 1261 cgggtgaacg aggaccccaa ggacacactg ctgcgggaat tccaagagga gattgcccgc
104 1321 ctgaaggccc agctggagaa gagggggatg ctggggaagc ggccccggag gaagagcagc
105 1381 cgcaggaaga aggccgtgtc cgccccgcct gggtaccctg agggcccagt gattgaggct
106 1441 tgggtggcag aagaggagga tgacaacaac aacaaccacc gcccgcccca gcccatcctg
107 1501 gagtcagcct tggagaagaa catggagaat tacctgcagg aacagaagga gcggctggag
108 1561 gaggagaagg cagccatcca ggatgaccgc agcctggtga gcgaggagaa gcagaagctg
109 1621 ctggaggaga aggagaagat gctggaggac ctgcggcggg aacagcaggc cacagagctg
110 1681 cttgcggcca agtacaaggc catggagagc aagctcctca tcgggggcag gaacatcatg
111 1741 gatcacacca acgaacagca gaagatgttg gaactgaaga ggcaggagat tgccgagcag
112 1801 aaacgtcgtg agcgggagat gcagcaggag atgatgctcc gggacgagga gactatggag
113 1861 ctccggggca cctacacatc cctgcagcag gaggtggagg tcaaaaccaa gaaactcaag
114 1921 aagctctacg ccaagctgca ggcggtgaag gcggagatcc aggaccagca tgatgagtat
115 1981 atccgcgtgc ggcaggacct ggaggaggcg cagaacgagc agacccgcga actcaagctc
116 2041 aagtacctaa tcatcgagaa cttcatcccg ccggaggaga agaacaagat catgaaccgg
117 2101 cttttcctgg actgtgagga ggagcagtgg aagttccagc cactggtgcc agccggcgtc
118 2161 agtagcagcc agatgaagaa gcggccaaca tctgcagtgg gctacaagag gcctatcagc
119 2221 cagtatgctc gggttgccat ggcaatgggg tcccacccca ggtacagggc tgaaaacata
120 2281 atgtttctgg agttggatgt gtcccctcca gctgtctttg agatggaatt ctctcacgac
121 2341 caagaacaag accctcgtgc gctacacatg gagaggctca tgcgattgga cagctttctg
122 2401 gaaagacctt ccacgtctaa agtccgaaag tccagatcct ggtgccagag tcctcagcgg
123 2461 cctccacctt ccaccacaca tgcctccctg gcctctgctt ctctgcgccc tgcaacagtg
124 2521 gcggaccatg agtgacaacc atcacgtcag gctgcccatc caatagactc ctgggatggg
125 2581 gcagccaacc ctggctcatc tcatctgccg cttggtgcgt gtgcgtgtgc gtgcatgtgc
126 2641 gtgtgcgtgt gtgcaggggt gagaatctgg cagatggtgc ctctgcctgc tcttcttcgc
127 2701 ctcctttatt taattcatgt tatttattcg cggacgtctg ttcgtgttgg ggagatgccc
128 2761 tcgcctgagc cgtctgggcc taccgtggtc actgcgtacg ctctttttct tctgacttga
129 2821 gagctccccc agtcagatct caggcttgtc cccctgtcag ctgcctccag aagggaaggt
130 2881 agccagtgcc tgagaagaca gtcccttttc tacccaccgc actccataac ctccatcttc
131 2941 tcccacactg atggcgagca gcccctgagc actttctggg actgggagac tgcttggtgt
132 3001 tccctgagga caagagacat cctgacagtg ttgggcatct gctccccgtg gacacagccc
133 3061 cactctccac tttctgagcc tcagacaacc tcattcagcc tcttgggctc cttttcaagg
134 3121 acattaataa cctcaccaac atagctcatg cccttcagct ttgacaagaa ctcacggctt
135 3181 cccaaactct gctttctgcc caccttggat gggaactgtg gaccaagcaa ttaccatcgc
136 3241 cttggaacct gcaggaaatg gaacagcaat tgagacaact tgaacagtca tcaacggaag
137 3301 tccctccact ggattccttt gtttctgtcc cctccgagga gtcattttgg tcgacaggct
138 3361 ctcaaggcaa ctccccattt tcaagaggct gctcctgcct gcttcgatca tttctccctg
139 3421 cagctgccta gaccccgttc acagtgggag gagtcaatgt cattctaccc ctcgctaaac
140 3481 gaagatatta acatctattg ctttttccct tcatctgtca caggaaacag aagcccaggc
141 3541 acaatctttt ccagctttgc ctgttacccc tgtttctgaa ttgcatcttt aaggtattat
142 3601 tttgttgaca atagatcctt tattcactag ttacgcaaat tggttcctag ggggatactc
143 3661 cttaccttcc tttgtgatgg cccaaaatgt ctctaggtat ctcaagtgat aagtaaattt
144 3721 ctacaaaaaa aaaatggtta atgttcattg actggctttt taagtgtata ttttggagga
145 3781 cgggtgaaga ggtcataacg aaagcaagcg agtgaattag gatttcaaag tgccctaata
146 3841 gtgtgagtct ccagttccta gaatatgaag agtgctgtcg ttggggtgaa accatgagac
147 3901 tgacagatct gcctgaaatg gggggtgtgg gaggtggtgg cgggggttat tctctttcct
148 3961 tcaggaaatg aacccttctt acatcattca agttctgctc tgaggatcaa gcttgggtct
149 4021 gatttaactc agcgacactg tcatttctgc ttcattactg gactagaggg ttgagccacc
150 4081 cacttgccat ttgctcctgt ccttccagga aatcacaatt ttcatcagag cccaagagat
151 4141 tatttgagac tcaggattca gatcagaggt tcgactgtgg ctgggacagg agttgtgtgt
152 4201 agaaattcac caggtggcct gagcgcaggg ggacctccag gctgcgttga gcagcctctc
153 4261 ccactgacct ctttctcgtt tgtggacaaa gcagcacgta tcacctcatt catcacttgg
154 4321 acacatcgcc tttgcattgt cttgtcacac ctccctcaca gtcttatagc acaatatacc
155 4381 caaatcagcc cccccagtcc gaggctgggc ccaaggtatg gtcggaggag gagctcctgc
156 4441 ctgcggtttt gtgtatgtgt gtatgtgtgt gcgtgtttgt gtgcgtgttt acctccacag
157 4501 gggacactct acactcagtg taagatctgc tgggaacagg gccaccagga gtgcgtggat
158 4561 ctcagtctct ctgtctctct ttctctcctt ttaattttgg tgtatcaaat atttgattga
159 4621 caaagtaagg gccttgatta ggaccaaatt ctcgtgtgtt gctatggtct ttatttagga
160 4681 caacaattaa caatgcagtg gcccattctt gtcactctac acatatgact atacgggaca
161 4741 tatgtaatat ataaatatat atataaaaca ttcccctctg tccccttggc ttcggatgga
162 4801 ggaatttctg ttgagctgaa atgcacctgc agctgggtgc tgccagcagc ttgcaggccc
163 4861 cagccctgtt ccaatcaatg cagttgacaa taaaggaatg agtatcgtca cgg