| blob | 026dd2502612f42a831335330c2b9d5371c8091c |
2 ID AGA000066 standard; DNA; INV; 5195 BP.
3 XX
4 AC BN000066;
5 XX
6 SV BN000066.1
7 XX
8 DT 07-OCT-2002 (Rel. 73, Created)
9 DT 21-NOV-2002 (Rel. 73, Last updated, Version 11)
10 XX
11 DE TPA: Anopheles gambiae achE1 gene for acetylcholinesterase, exons 1-6
12 XX
13 KW acetylcholinesterase; achE1 gene; Third Party Annotation; TPA.
14 XX
15 OS Anopheles gambiae (African malaria mosquito)
16 OC Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera;
17 OC Endopterygota; Diptera; Nematocera; Culicoidea; Anopheles.
18 XX
19 RN [1]
20 RP 1-5195
21 RA Fort P.P.;
22 RT ;
23 RL Submitted (30-NOV-2001) to the EMBL/GenBank/DDBJ databases.
24 RL Fort P.P., CRBM-UPR1086, Cnrs, 1919 route de Mende, 34293 MONTPELLIER CEDEX
25 RL 5, FRANCE.
26 XX
27 RN [3]
28 RA Weill M., Fort P., Berthomi eu A., Dubois M.P., Pasteur N., Raymond M.;
29 RT "A novel acetylcholinesterase gene in mosquitoes codes for the insecticide
30 RT target and is non-homologous to the ace gene in Drosophila";
31 RL Proc. R. Soc. Lond., B, Biol. Sci. 269:2007-2016(2002).
32 XX
33 CC see also AJ488492 for achE-1 from Kisumu strain
34 CC Third Party Annotation Database: This TPA record uses Anopheles gambiae
35 CC trace archive data (http://trace.ensembl.org)
36 XX
37 AH TPA_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
38 AS 1-685 TI55475028 11-685
39 AS 1-747 TI47553499 11-747
40 AS 1-800 TI55407518 11-800
41 AS 188-895 TI57630934 11-707
42 AS 223-845 TI57283198 11-622
43 AS 251-895 TI47098900 11-644
44 AS 272-999 TI56725015 11-727
45 AS 387-1193 TI57310066 11-806
46 AS 431-1195 TI56845856 11-764
47 AS 522-1220 TI55215818 11-698
48 AS 546-1208 TI57401582 11-661
49 AS 566-1208 TI56169014 11-642
50 AS 584-1306 TI59761948 11-722
51 AS 738-1306 TI55852606 11-568
52 AS 827-1634 TI57602219 11-807
53 AS 1064-1769 TI44966390 11-705
54 AS 1065-1822 TI60742945 11-757
55 AS 1129-1954 TI56042882 11-825
56 AS 1223-1979 TI60461178 11-756
57 AS 1226-1868 TI56472916 11-642
58 AS 1296-1989 TI44952509 11-693
59 AS 1364-2170 TI56006358 11-806
60 AS 1561-2341 TI58704241 11-780
61 AS 1582-2385 TI44875600 11-803
62 AS 1740-2415 TI55894404 11-675
63 AS 1794-2585 TI56056818 11-791
64 AS 1834-2644 TI47256770 11-809
65 AS 1848-2729 TI56446066 11-879
66 AS 1849-2515 TI44984669 11-665
67 AS 2216-3002 TI57417259 11-786
68 AS 2224-3029 TI56867244 11-805
69 AS 2226-3057 TI59803037 11-831
70 AS 2299-3083 TI60503347 11-784
71 AS 2614-3351 TI44891398 11-736
72 AS 2654-3419 TI55336738 11-765
73 AS 2663-3304 TI60709914 11-641
74 AS 2672-3417 TI56453591 11-745
75 AS 2691-3260 TI55690247 11-569
76 AS 2697-3494 TI55745954 11-797
77 AS 2885-3706 TI58733608 11-821
78 AS 2896-3700 TI58130218 11-803
79 AS 2946-3741 TI56432498 11-795
80 AS 2992-3702 TI47561255 11-710
81 AS 2992-3702 TI55208429 11-710
82 AS 3029-3807 TI47256418 11-778
83 AS 3030-3831 TI47233061 11-801
84 AS 3123-3892 TI55870944 11-769
85 AS 3255-4043 TI47465031 11-787
86 AS 3325-4045 TI55382589 11-720
87 AS 3535-4255 TI46993841 11-720
88 AS 3574-4244 TI56607077 11-670
89 AS 3596-4394 TI56526265 11-798
90 AS 3704-4484 TI56050293 11-780
91 AS 3724-4560 TI59807029 11-836
92 AS 3745-4549 TI55159438 11-804
93 AS 3753-4596 TI56586965 11-842
94 AS 3800-4577 TI56592754 11-777
95 AS 3833-4635 TI47243257 11-801
96 AS 3837-4272 TI59628661 11-435
97 AS 3899-4728 TI56895999 11-829
98 AS 3938-4704 TI59830483 11-766
99 AS 3942-4704 TI55700050 11-762
100 AS 4116-4912 TI56961976 11-796
101 AS 4137-4761 TI46929238 11-623
102 AS 4148-4961 TI59909853 11-813
103 AS 4285-5046 TI47085450 11-759
104 AS 4315-5069 TI58096045 11-754
105 AS 4387-5177 TI58084392 11-790
106 AS 4455-5175 TI55094688 11-720
107 AS 4455-5195 TI55297322 11-740
108 AS 4491-5195 TI56990277 11-704
109 XX
110 FH Key Location/Qualifiers
111 FH
112 FT source 1..5195
113 FT /db_xref="taxon:7165"
114 FT /organism="Anopheles gambiae"
115 FT CDS join(<1780..1914,2001..2538,2618..2815,2902..3609,
116 FT 3676..3848,3956..4077)
117 FT /codon_start=3
118 FT /gene="achE1"
119 FT /product="acetylcholinesterase"
120 FT /EC_number="3.1.1.7"
121 FT /function="hydrolyzes acetylcholine at cholinergic
122 FT synapses"
123 FT /protein_id="CAD29865.2"
124 FT /translation="AFFTPYIGHGESVRIIDAELGTLEHVHSGATPRRRGLTRRESNSD
125 FT ANDNDPLVVNTDKGRIRGITVDAPSGKKVDVWLGIPYAQPPVGPLRFRHPRPAEKWTGV
126 FT LNTTTPPNSCVQIVDTVFGDFPGATMWNPNTPLSEDCLYINVVAPRPRPKNAAVMLWIF
127 FT GGGFYSGTATLDVYDHRALASEENVIVVSLQYRVASLGFLFLGTPEAPGNAGLFDQNLA
128 FT LRWVRDNIHRFGGDPSRVTLFGESAGAVSVSLHLLSALSRDLFQRAILQSGSPTAPWAL
129 FT VSREEATLRALRLAEAVGCPHEPSKLSDAVECLRGKDPHVLVNNEWGTLGICEFPFVPV
130 FT VDGAFLDETPQRSLASGRFKKTEILTGSNTEEGYYFIIYYLTELLRKEEGVTVTREEFL
131 FT QAVRELNPYVNGAARQAIVFEYTDWTEPDNPNSNRDALDKMVGDYHFTCNVNEFAQRYA
132 FT EEGNNVYMYLYTHRSKGNPWPRWTGVMHGDEINYVFGEPLNPTLGYTEDEKDFSRKIMR
133 FT YWSNFAKTGNPNPNTASSEFPEWPKHTAHGRHYLELGLNTSFVGRGPRLRQCAFWKKYL
134 FT PQLVAATSNLPGPAPPSEPCESSAFFYRPDLIVLLVSLLTATVRFIQ"
135 FT mRNA join(<1780..1914,2001..2538,2618..2815,2902..3609,
136 FT 3676..3848,3956..>4596)
137 FT /gene="achE1"
138 FT exon <1780..1914
139 FT /number=1
140 FT /gene="achE1"
141 FT intron 1915..2000
142 FT /number=1
143 FT /gene="achE1"
144 FT exon 2001..2538
145 FT /number=2
146 FT /gene="achE1"
147 FT intron 2539..2617
148 FT /number=2
149 FT /gene="achE1"
150 FT exon 2618..2815
151 FT /number=3
152 FT /gene="achE1"
153 FT intron 2816..2901
154 FT /number=3
155 FT /gene="achE1"
156 FT exon 2902..3609
157 FT /number=4
158 FT /gene="achE1"
159 FT intron 3610..3675
160 FT /number=4
161 FT /gene="achE1"
162 FT exon 3676..3848
163 FT /number=5
164 FT /gene="achE1"
165 FT intron 3849..3955
166 FT /number=5
167 FT /gene="achE1"
168 FT exon 3956..>4596
169 FT /number=6
170 FT /gene="achE1"
171 FT polyA_signal 4628..4633
172 FT /gene="achE1"
173 XX
174 SQ Sequence 5195 BP; 1326 A; 1468 C; 1183 G; 1218 T; 0 other;
175 gaggtggatt ggtacggatt ggtcatttcc gttcttcttc atgtgcgttt cttactctcc 60
176 tgccttctca aacgaacttc agaacgaaaa aaaacacgcg acggagagta agaagctgta 120
177 cagacactct agtcctcaca cacacaactt gcttactttg tccgtccgtt tgattccgct 180
178 ctttctatgt gtgactttct ggcacccttt acttcgtcac tattcatttc atttccaata 240
179 aacttttaat gtgtctttct tttttattct aaatatctat agtaaatgtt ctgtagcaag 300
180 tatcttgtag tagaattgta tagaagtaga tttttgtatg agtttgcatc atcccttccc 360
181 aatggggttg actccgtttc aaccaacgcc aaaagctatc ggcataaagt atggttcctt 420
182 gcaaaggctt ttatgaaaca cgaatgtgtt gaaagctttt gcaaatggaa atgttaaagc 480
183 ctttaagttc caatcgcttt ttgtatccat ttagtttgca tgaacaacag gaaatcaaaa 540
184 tattggtaac gacaatcgct ggcgggcgtt cctttcttgt ctaatcaaat catctacgat 600
185 tgtaattaca aacttccaag tttgcgtatg acaatgttaa atgtctaaga cgctcaaatg 660
186 caaccaatag agtataatta ctaaggcggg cagtagaaac caaaatatct taaataatgt 720
187 caagcaaaac aaaaagaaca attccgttca ctgctcaaag aaagccctaa ctaactacct 780
188 aaccttttca tcgatgaccc tgtactgaca tggtaagata ttctttatcc tttaactctt 840
189 ctgcacccta cgcactcaat gcaacacacg cactactatt actgctacta ctctcgcact 900
190 cacgagcacc tacttgcact caagccggca ctcaatgtac tagcgaaaca cgtcgcatct 960
191 aagcactcac aaggaagcac acatttgcaa atagcaccta ccggaacagc tttgaatgtg 1020
192 ccagcacagc attgaacagg ttcgcgcctt tactcctgtg ctctgttttc tcgatcggaa 1080
193 tgttcgaaag ttgaaaagcg cattttttca tctctctttt tctattcttc ttcgtatttt 1140
194 tatccctctc tcgtcgtgtt ttttctaaac attaccatac ttcttccgct acgaactcgc 1200
195 caagaaccag aacgcagcgt gcgtgcggtg cttgcggtgt gtgtgtgtgt gtgtgtattc 1260
196 cacggctgcg agaagcaaga tcggagaaca ggcatcattc ccctttcaca gacaattgca 1320
197 cttttgtact agaacagaaa acgagacagc ataatttcca acagcctcat tcactcatac 1380
198 caggctcaca ccgactttta accgaaacat gtactacaga aacaaaaaca aacaatatgg 1440
199 agagtgctcg cgctgatact aagttaatat gaagagatta ctggcgaggt catcgatccc 1500
200 atcccgacat catcgctcca ggctccagac ctaccaagtc gcctaccatt acctacccac 1560
201 caccgaccac tactcacaca gcattatcac ttccgccgcc gtcgccgccg ccgccgacgc 1620
202 cgccgacgcc accaccttca caccgccctg ccaaaatgaa tgcgcattgt tgcgatagat 1680
203 tgaatttcct tggttgttgt tgttgttggt tttcttttga catgtttgtg tgttgttttt 1740
204 tctttctctc tctctctttc tgtggttcca acatttcaga cgcatttttt acaccatata 1800
205 taggtcacgg tgagtccgta cgaattatag atgccgagtt gggcacgctc gagcatgtcc 1860
206 acagtggagc aacgccgcgg cgacgcggcc tgacgaggcg cgagtcaaac tcgggtaagt 1920
207 acgcgattgg aagtgggggg acgtttaccc taccgtgtac tactacaacg cactttaccc 1980
208 ccacgcacac gcaccggcag acgcgaacga caacgatccg ctggtggtca acacggataa 2040
209 ggggcgcatc cgcggcatta cggtcgatgc gcccagcggc aagaaggtgg acgtgtggct 2100
210 cggcattccc tacgcccagc cgccggtcgg gccgctacgg ttccgtcatc cgcggccggc 2160
211 cgaaaagtgg accggcgtgc tgaacacgac cacaccgccc aacagctgcg tgcagatcgt 2220
212 ggacaccgtg ttcggcgact tcccgggcgc gaccatgtgg aacccgaaca cgcccctgtc 2280
213 cgaggactgt ctgtacatta acgtggtggc accgcgaccc cggcccaaga atgcggccgt 2340
214 catgctgtgg atcttcggcg gcggcttcta ctccggcacc gccaccctgg acgtgtacga 2400
215 ccaccgggcg cttgcgtcgg aggagaacgt gatcgtggtg tcgctgcagt accgcgtggc 2460
216 cagtctgggc ttcctgtttc tcggcacccc ggaagcgccg ggcaatgcgg gactgttcga 2520
217 tcagaacctt gcgctacggt aggtgtcttt gcatgtgtga atgagggtat agtattctaa 2580
218 cgaggtgctc ttcttcccat cacttcttgg gagtcagctg ggtgcgggac aacattcacc 2640
219 ggttcggtgg cgatccgtcg cgtgtgacac tgttcggcga gagtgccggt gccgtctcgg 2700
220 tgtcgctgca tctgctgtcc gccctttccc gcgatctgtt ccagcgggcc atcctgcaga 2760
221 gcggctcgcc gacggcaccg tgggcattgg tatcgcgcga ggaagccaca ctaaggtacg 2820
222 tgccagctgc tgctttcccc aaaccaccaa cccgcaacag ctcacacaac cctcttttcc 2880
223 gtcgctcttt tctcgctcca gagcactgcg gttggccgag gcggtcggct gcccgcacga 2940
224 accgagcaag ctgagcgatg cggtcgagtg cctgcgcggc aaggacccgc acgtgctggt 3000
225 caacaacgag tggggcacgc tcggcatttg cgagttcccg ttcgtgccgg tggtcgacgg 3060
226 tgcgttcctg gacgagacgc cgcagcgttc gctcgccagc gggcgcttca agaagacgga 3120
227 gatcctcacc ggcagcaaca cggaggaggg ctactacttc atcatctact acctgaccga 3180
228 gctgctgcgc aaggaggagg gcgtgaccgt gacgcgcgag gagttcctgc aggcggtgcg 3240
229 cgagctcaac ccgtacgtga acggggcggc ccggcaggcg atcgtgttcg agtacaccga 3300
230 ctggaccgag ccggacaacc cgaacagcaa ccgggacgcg ctggacaaga tggtgggcga 3360
231 ctatcacttc acctgcaacg tgaacgagtt cgcgcagcgg tacgccgagg agggcaacaa 3420
232 cgtctacatg tatctgtaca cgcaccgcag caaaggcaac ccgtggccgc gctggacggg 3480
233 cgtgatgcac ggcgacgaga tcaactacgt gttcggcgaa ccgctcaacc ccaccctcgg 3540
234 ctacaccgag gacgagaaag actttagccg gaagatcatg cgatactggt ccaactttgc 3600
235 caaaaccggg taagtgtgtg tgtcaaacag cagagtgtcg atcgctctaa caccagcgtc 3660
236 ttctctcttc tacagcaatc caaatcccaa cacggccagc agcgaattcc ccgagtggcc 3720
237 caagcacacc gcccacggac ggcactatct ggagctgggc ctcaacacgt ccttcgtcgg 3780
238 tcggggccca cggttgaggc agtgtgcctt ctggaagaag taccttcccc agctagttgc 3840
239 agctacctgt aagtctcgtg cagcacttga aaccccctcc cacatcccca tcagggtcca 3900
240 ggttgcaata ataaatttca ctttctctct ctcacgtctc ttttccccaa aacagcgaac 3960
241 ctaccagggc cagcaccgcc tagtgaaccg tgcgaaagca gcgcattttt ttaccgacct 4020
242 gatctgatcg tgctgctggt gtcgctgctt acggcgaccg tcagattcat acaataatta 4080
243 ctaccccatc catggcctag ttcgtttaag ctttaagata gtgaggaaca aatttttccc 4140
244 aaacaatttt ccccccttta gagcagaacc gagggagaga taggactaca tagcgaaaag 4200
245 ggaaaacaag tggtggcgga cgaggagaga agaagcaaat cgaataatcg aagcaacaac 4260
246 aacaacaaca aaaaaactgc aaccgggttc actaaaccca gggggcagct cagtagcaaa 4320
247 ctactactta aataactact ttcttatggc aaattatggc aagagcagtc gtgatgggtt 4380
248 cgatcagtat ccatctgacc ggagcagctg aaccgtttca tgggcagttg ctgcaataca 4440
249 ccacgacccg tacacacagt aacacacttt ttatagcttt acactaacaa ccactctccc 4500
250 cacgctcctc ttccccttcc cctccacaca gacagcagcg ccgtttgtag caggatctac 4560
251 taccgtgcgg tttggtatgg cggccaacaa cactaaacac cacacatcta ctaaaacaca 4620
252 ccggaacaat aaacaaatgt taaacttact atatgaatat acatctagac gcatatatac 4680
253 gcatgaacta ctacttccct cgtgttctga caaaacacat taccttgtcc cccctccccc 4740
254 tccggtttgc ttaccaccac tgcaccacca gtatgaattt gttccataat aacgcttcgt 4800
255 aactcgttac caggagcaca actgggtcgt tggcggagtg ctgcgcgttt cgtgctgaag 4860
256 atgtaaacta gcaccgcgca cactttcgac acgcaaccac agctacacat cacgaaagca 4920
257 acatcctggc cctatccgtt ttctcattct taaaacttct ttccttagac caaaaccaac 4980
258 gcaaactagc aaaaggtact tgagtaaccg gtccagtaca cactgtgcta caattgagcg 5040
259 tagggaggag gtataatttc tgcaaaatgt ataaaacaaa actaaaacaa actaattact 5100
260 tgcaatccat tctaaagcac gaaaactcct caaaataaaa acgggaagta aacaaaaaaa 5160
261 tcagaacgaa caaatttacc taaaaaaaag taaac 5195
262 //