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 115 <div class="style1" align="right">Download</div>
 116 </div>
 117 <div id="Layer2"
 118  style="position: absolute; left: 226px; width: 497px; z-index: 2; top: 188px; height: 877px;">
 119 <h3 class="heading1">Download</h3>
 120
 121 <p style="text-align: justify;">
 122
 123 PsN is distributed  as a gziped tar ball and zipped file. Both should work
 124 on Windows and UNIX (Including Linux an OS X).</p>
 125
 126 <table style="width: 100%;" border="0" cellpadding="4" cellspacing="4">
 127   <tbody>
 128 <!--    <tr>
 129       <td>
 130       <p><a href="http://prdownloads.sourceforge.net/psn/PsN-2.1.10.tar.gz?download" target="_blank">PsN-2.1.10.tar.gz</a></p>
 131       </td>
 132       <td>
 133       <p>This is the latest development release.</p>
 134       </td>
 135       <td>
 136       <p>2005-10-14</p>
 137       </td>
 138     </tr>
 139     <tr>
 140       <td>
 141       <p><a href="http://prdownloads.sourceforge.net/psn/PsN-2.1.10.zip?download" target="_blank">PsN-2.1.10.zip</a></p>
 142       </td>
 143       <td>
 144       <p>This is the latest development release.</p>
 145       </td>
 146       <td>
 147       <p>2005-10-14</p>
 148       </td>
 149     </tr> -->
 150     <tr>
 151       <td colspan="3">
 152       <p><b>Latest stable release</b></p>      </td>
 153     </tr>
 154     <tr>
 155       <td colspan="3">
 156           <tr>
 157       <td width="27%"><p><a href="http://prdownloads.sourceforge.net/psn/PsN-2.2.4.tar.gz?download" target="_blank">PsN-2.2.4.tar.gz</a></p></td>
 158       <td width="55%">Please see the <a href="http://sourceforge.net/project/shownotes.php?group_id=101419&release_id=537859">change log</a> or the README.txt file for details. </td>
 159       <td width="18%"><p>2007-09-10</p></td>
 160     </tr>
 161     <tr>
 162       <td><p><a href="http://prdownloads.sourceforge.net/psn/PsN-2.2.4.zip?download" target="_blank">PsN-2.2.4.zip</a></p></td>
 163       <td><p>&nbsp;</p></td>
 164       <td><p>2007-09-10</p></td>
 165     </tr>
 166     <tr>
 167       <td colspan="3">
 168       <p><b>Older releases</b></p></td>
 169     </tr>
 170     <tr>
 171       <td colspan="3">
 172           <tr>
 173       <td width="27%"><p><a href="http://prdownloads.sourceforge.net/psn/PsN-2.2.3.tar.gz?download" target="_blank">PsN-2.2.3.tar.gz</a></p></td>
 174       <td width="55%">Please see the <a href="http://sourceforge.net/project/shownotes.php?group_id=101419&release_id=504936">change log</a> or the README.txt file for details. </td>
 175       <td width="18%"><p>2007-04-30</p></td>
 176     </tr>
 177     <tr>
 178       <td><p><a href="http://prdownloads.sourceforge.net/psn/PsN-2.2.3.zip?download" target="_blank">PsN-2.2.3.zip</a></p></td>
 179       <td><p>&nbsp;</p></td>
 180       <td><p>2007-04-30</p></td>
 181     </tr>
 182     <tr>
 183       <td><p><a href="http://prdownloads.sourceforge.net/psn/PsN-2.2.2.tar.gz?download" target="_blank">PsN-2.2.2.tar.gz</a></p></td>
 184       <td>Includes a rather large re-write of the jobs submission. Memory foot print should be much lower.  See the README.txt for details.</td>
 185       <td><p>2007-03-05</p></td>
 186     </tr>
 187     <tr>
 188       <td><p><a href="http://prdownloads.sourceforge.net/psn/PsN-2.2.2.zip?download" target="_blank">PsN-2.2.2.zip</a></p></td>
 189       <td><p>&nbsp;</p></td>
 190       <td><p>2007-03-05</p></td>
 191     </tr>
 192     <tr>
 193       <td colspan="3">
 194           <tr>
 195         <td><p><a href="http://prdownloads.sourceforge.net/psn/PsN-2.2.1.tar.gz?download" target="_blank">PsN-2.2.1.tar.gz</a></p></td>
 196             <td><p>Version 2.2.1</p></td>
 197             <td><p>2006-11-07</p></td>
 198       </tr>
 199           <tr>
 200         <td><p><a href="http://prdownloads.sourceforge.net/psn/PsN-2.2.1.zip?download" target="_blank">PsN-2.2.1.zip</a></p></td>
 201             <td><p>&nbsp;</p></td>
 202             <td><p>2006-11-07</p></td>
 203       </tr>
 204           <tr>
 205         <td><p><a href="http://prdownloads.sourceforge.net/psn/PsN-2.2.0.tar.gz?download" target="_blank">PsN-2.2.0.tar.gz</a></p></td>
 206             <td><p>The new 2.2.0 release</p></td>
 207             <td><p>2006-08-09</p></td>
 208       </tr>
 209           <tr>
 210         <td><p><a href="http://prdownloads.sourceforge.net/psn/PsN-2.2.0.zip?download" target="_blank">PsN-2.2.0.zip</a></p></td>
 211             <td><p>&nbsp;</p></td>
 212             <td><p>2006-08-09</p></td>
 213       </tr>
 214
 215
 216     <tr>
 217       <td colspan="3" style="vertical-align: top;"><p>&nbsp;</p></td>
 218     </tr>
 219     <tr>
 220       <td colspan="3">
 221       <p><b>Beta releases</b></p></td>
 222     </tr>
 223     <tr>
 224       <td colspan="3">
 225           <tr>
 226         <td colspan="3" style="vertical-align: top;"><p>We have begun to release beta tests of the stable releases. In these we will include all bug fixes and feature additions  that we think are suitable to add quickly to the stable branch. </p></td>
 227       </tr>
 228           <tr>
 229       <td><p><a href="http://prdownloads.sourceforge.net/psn/PsN-2.2.2-beta4.tar.gz?download" target="_blank">PsN-2.2.2-beta4.tar.gz</a></p></td>
 230       <td><p>4:th beta of the 2.2.2 release. Please use the stable release 2.2.3. It is newer than this beta release. </p></td>
 231       <td><p>2007-01-29</p></td>
 232     </tr>
 233     <tr>
 234       <td><p><a href="http://prdownloads.sourceforge.net/psn/PsN-2.2.2-beta4.zip?download" target="_blank">PsN-2.2.2-beta4.zip</a></p></td>
 235       <td><p>&nbsp;</p></td>
 236       <td><p>2007-01-29</p></td>
 237     </tr>
 238     <tr>
 239       <td colspan="3" style="vertical-align: top;"><p>&nbsp;</p></td>
 240     </tr>
 241     <tr>
 242       <td colspan="3" style="vertical-align: top;"><p><b>PsN Development release</b></p></td>
 243     </tr>
 244     <tr>
 245       <td colspan="3" style="vertical-align: top;"><p>There is currently no development version available, but we are
 246           planning to implement some interresting features and a release
 247           of 2.3.0 might appear here then.</p></td>
 248     </tr>
 249   </tbody>
 250 </table>
 251
 252 <p>&nbsp;</p>
 253 <h3 class="heading1">Version numbers</h3>
 254
 255 <p style="text-align: justify;">
 256
 257 The PsN project follows the Linux style version numbering. The format
 258 is X.Y.Z where X is major version. The Y is minor version and
 259 increases when significant features are added or changed. The minor
 260 version is even for stable release, and odd for development
 261 releases. The Z is a revision number, it changes more often and
 262 signifies smaller changes, mostly bug fixes.<br> </p>
 263
 264 <p style="text-align: justify;">
 265
 266 Older PsN versions is available from the <a target="_blank"
 267 href="http://sourceforge.net/projects/psn/">SourceForge project
 268 page</a>. (Look under the <a
 269 href="http://sourceforge.net/project/showfiles.php?group_id=101419">files</a>
 270 section). The project page also explains how to access the SourceForge
 271 CVS, the repository where the latest changes to PsN are stored. However, if you
 272 download PsN from the CVS the stability is not guaranteed - it might
 273 be broken. </p>
 274
 275 <h3 class="heading1">Compatibility<br> </h3>
 276
 277 <p align="justify">PsN is tested on various platfiorms.
 278 <table width="499" border="1">
 279   <tr>
 280     <th scope="col">&nbsp;</th>
 281     <th scope="col">Operating system version </th>
 282     <th scope="col">Perl</th>
 283     <th scope="col">NONMEM</th>
 284     <th scope="col">Fortran compiler </th>
 285   </tr>
 286   <tr>
 287     <th scope="row">Microsoft Windows</th>
 288     <td>XP</td>
 289     <td><a target="_blank"
 290  href="http://www.activestate.com/Products/ActivePerl/">ActiveState</a> ActivePerl 5.6.8.811 and 5.8.8.819 </td>
 291     <td>5 and 6 </td>
 292     <td><a
 293 target="_blank" href="http://www.qtsoftware.de/dvf/">Digital Visual
 294   Fortran</a> version 6.5 </td>
 295   </tr>
 296   <tr>
 297     <th scope="row">&nbsp;</th>
 298     <td>2000</td>
 299     <td><a target="_blank"
 300  href="http://www.activestate.com/Products/ActivePerl/">ActiveState</a> ActivePerl 5.6.8.811 and 5.8.8.819 </td>
 301     <td>5 and 6</td>
 302     <td><a
 303 target="_blank" href="http://www.qtsoftware.de/dvf/">Digital Visual
 304   Fortran</a> version 6.5</td>
 305   </tr>
 306   <tr>
 307     <th scope="row">Macintosh</th>
 308     <td>OS X 10.4.7 and above </td>
 309     <td>5.8.6 and 5.8.8</td>
 310     <td>5 and 6</td>
 311     <td>Intel Fortran 9.1 </td>
 312   </tr>
 313   <tr>
 314     <th scope="row">Linux</th>
 315     <td>Red Hat 9, Gentoo </td>
 316     <td>&nbsp;</td>
 317     <td>5 and 6</td>
 318     <td><a target="_blank"
 319 href="http://www.gnu.org">GNU</a> g77 2.96 and 3.3 </td>
 320   </tr>
 321   <tr>
 322     <th scope="row">&nbsp;</th>
 323     <td>&nbsp;</td>
 324     <td>&nbsp;</td>
 325     <td>&nbsp;</td>
 326     <td>&nbsp;</td>
 327   </tr>
 328 </table>
 329 <p align="justify">
 330
 331 <p align="justify">
 332
 333 Our aim is to make PsN platform independent. Please try
 334 PsN on other platforms and with other Perl versions and compilers and
 335 report your success or failure.
 336 <h3 class="heading1">Installation instructions<br> </h3>
 337
 338 <p>Installation is easy and consists of five simple
 339 steps.</p>
 340
 341 <p style="font-weight: bold;">Installation using the provided setup
 342 script</p> <ol>
 343   <li>
 344     <p>Unpack the file you downloaded. It will create a directory
 345        called <tt>PsN-Source.</tt></p>
 346   </li>
 347   <li>
 348     <div style="text-align: justify;">
 349
 350     <p align="justify">Run the installation script from within <tt>PsN-Source</tt>.
 351        If you are running windows and have <a target="_blank"
 352  href="http://www.activestate.com/Products/ActivePerl/">ActiveState
 353       ActivePerl</a> installed you should be able to double-click on
 354       <tt>setup.pl</tt>. Otherwise open a command line window (Windows Start-&gt;Run, type 'cmd'), go to
 355       the <tt>PsN-Source </tt>directory and type: </p>
 356     </div>
 357     <p><tt>perl setup.pl</tt></p>
 358     <p>Unix users should open their favorite terminal go to the <tt>PsN-Source</tt> directory and type: </p>
 359     <p><tt>perl setup.pl</tt></p>
 360   </li>
 361   <li style="text-align: justify;">
 362
 363     <p>Answer the questions on screen. The default is probably the
 364        best for most users. If you cannot install PsN where the install
 365        script suggests and you wish to use PsN in your own perl
 366        scripts, you must make sure that the directory where you
 367        installed the PsN core and toolkit is in Perl's include
 368        path. For convenience you should also check that the directory
 369        where the utilities are installed is in your search path.      </p>
 370   </li>
 371   <li>
 372
 373     <p style="text-align: justify;">Edit the configuration file    <tt>psn.conf</tt> to make PsN aware your NONMEM
 374     installation. If you accept the default options in the PsN setup script, this file is usually found in C:\Perl\site\lib\PsN_version_number\ (Windows) or /usr/local/lib/perl5/site_perl/perl_version/PsN_version/ or /usr/lib/perl5/site_perl/perl_version/PsN_version/ (Linux and Macintosh). </p> <p> For a more detailed documentation of the psn.conf <a href="psn_conf.php">look here.</a></p>
 375
 376     <p><span style="font-family: monospace;">[nm_versions]</span><br style="font-family: monospace;">
 377       <span style="font-family: monospace;">default=/export/home/nmvi1.0,6 <br style="font-family: monospace;">
 378 5=/export/home/nmv1.1,5
 379       <br style="font-family: monospace;">
 380 5_big=/export/home/nmv1.1_big,5</span><br>
 381       <span style="font-family: monospace;">6=/export/home/nmvi1.0</span> <br style="font-family: monospace;">
 382       <span style="font-family: monospace;"></span><br style="font-family: monospace;">
 383       <span style="font-family: monospace;">[compiler]</span>
 384       <br style="font-family: monospace;">
 385       <span style="font-family: monospace;">; Gnu fortran compiler</span>
 386       <br style="font-family: monospace;">
 387       <span style="font-family: monospace;">name=g77</span>
 388       <br style="font-family: monospace;">
 389       <span style="font-family: monospace;">options=-W -static -O</span> </p>
 390   </li>
 391   <li><div style="text-align: justify;">
 392       <p>The header <tt>[nm_versions]</tt> must always be present. Each
 393         line under the <tt>nm_version</tt> header corresponds to a NONMEM version. To
 394         the left of the equal sign is an  identifier which is a number
 395         or a text that names an installation of NONMEM. This is what you give to the PsN utilities using the option <tt>-nm_version</tt>.
 396         Next comes the directory where the version of NONMEM is installed. Last is a version number. This is new from PsN version 2.2.2 and is needed for the computation of conditional weighted residuals. </p>
 397
 398     <p>The <tt>[compiler]</tt> section is optional but necessary if you have
 399       another compiler than g77. The <tt>compiler</tt> section has two
 400       lines. One starting with <tt>name</tt> on the left of the equal sign
 401       which is the compiler executable name. You should include a path if you
 402       don't have the compiler directory in you environment path. The second
 403       line is the <tt>options</tt> line where you specify compiler options,
 404       such as optimizations. (Note that
 405       lines starting with ; are ignored.)</p>
 406   </div>
 407   </li>
 408   <li>When the installation is
 409         done you can safely remove the <tt>PsN-Source</tt>
 410     directory if you like.</li>
 411   </ol>
 412 <br>
 413 <p style="font-weight: bold;">Manual installation</p>
 414 <p></p>
 415
 416 <p><b> As of version 2.2 we strongly encourage use of the installation
 417 script, it is stable and should work fine for most people. Should it
 418 fail for you, or have problems with installing an older PsN version, please contact us.</b> </p>
 419 <!--
 420  <ol>
 421   <li>
 422     <p>Unpack the file you downloaded. It will create a directory
 423 called <tt>PsN-Source.</tt></p>
 424   </li>
 425   <li>
 426     <p align="justify">Copy the <tt>PsN-Source\lib</tt> to a directory which is in the
 427 Perl include path. Make sure you name the directory <tt>PsN</tt>. Then
 428 copy the contents of <tt>PsN-Source\bin</tt> to a place that is in
 429 your systems path.
 430
 431 On my Windows installation of Perl I place the <tt>PsN-Source\lib</tt>
 432 directory in <tt>C:\perl\site\lib</tt>. And the contents of
 433 <tt>PsN-Source\bin</tt> in <tt>C:\perl\bin</tt>.
 434
 435 <p align="justify"> To get the Windows command line to recognize that the programs you
 436 just copied to <tt>C:\perl\bin</tt> you must create a batch file for
 437 each program. The easiest way is to just copy the <tt>runperl.bat</tt>
 438 that comes with ActiveState's Perl distribution. Make one copy for each
 439 program with the same name as the program but with the <tt>.bat</tt>
 440 extension.
 441 <p align="justify">
 442 For example, on a Gentoo Linux installation of Perl a good spot to place the
 443 <tt>PsN-Source\lib</tt> directory is in
 444 <tt>/usr/lib/perl5/site_perl/5.8.5</tt> and the
 445 <tt>PsN-Source\bin</tt> contents in <tt>/usr/bin</tt>
 446
 447     </p>
 448   </li>
 449   <li>
 450     <p align="justify">Next you must copy <span style="font-family:
 451 monospace;">PsN.pm</span> from the <tt>PsN-Source\lib</tt> to the
 452 directory just above the <tt>PsN</tt> you just created. Then you must
 453 edit it to find the PsN directory. The file looks something like this.<p align="justify">
 454
 455
 456 <span style="font-family: monospace;">package PsN;</span>
 457 <br style="font-family: monospace;">
 458 <span style="font-family: monospace;">use lib 'c:\perl\site\lib\PsN';</span>
 459 <br style="font-family: monospace;">
 460 <span style="font-family: monospace;">$config_file = "c:\perl\site\lib\PsN\psn.conf';</span>
 461 <br style="font-family: monospace;">
 462 <span style="font-family: monospace;">1;</span>
 463 <p align="justify">
 464 Now change the paths to where you installed PsN.<br>
 465     </p>
 466   </li>
 467   <li>
 468     <p align="justify">Edit the configuration, in the same way as in automatic
 469 installation.</p>
 470   </li>
 471   <li>
 472     <p align="justify">Install extra packages. At the time of writing, they are:</p>
 473   </li>
 474   <div align="justify">
 475
 476      <ul>
 477          <li> <a target="_blank"
 478  href="http://search.cpan.org/%7Egrommel/Math-Random-0.67/">Math::Random-0.67</a></li>
 479          <li><a target="_blank"
 480  href="http://search.cpan.org/%7Eams/Storable-2.13/">Storable::Store-0.67</a> (included with ActiveState Perl for Windows.)
 481         </li>
 482       </ul>
 483        <p align="justify">All are available from <a target="_blank"
 484  href="http://www.cpan.org/">CPAN.</a></p>
 485       </li>
 486   </div>
 487   <div align="justify"><li>When the installation is done you can safely remove the <tt>PsN-Source</tt>
 488 directory if you like.</div>
 489     </li>
 490   </ol>
 491 -->
 492 <p>&nbsp;</p>
 493 </div>
 494 <table border="0" cellpadding="0" cellspacing="0" width="780">
 495   <tbody>
 496     <tr>
 497       <td height="600" width="780">
 498       <table border="0" cellpadding="0" cellspacing="0" width="780">
 499         <tbody>
 500           <tr>
 501             <td colspan="7" height="201" width="780"><img
 502  src="images/indexpane1_1_.jpg" name="" alt="" border="0" height="201"
 503  width="780"></td>
 504           </tr>
 505           <tr>
 506             <td height="46" width="26"><img
 507  src="images/indexpane1_2_.jpg" name="" alt="" border="0" height="46"
 508  width="26"></td>
 509             <td height="46" width="73"><a href="index.php"
 510  onmouseover="changeImages(/*CMP*/ 'object', /*URL*/ 'images/indexhomeov.jpg'); return true;"
 511  onmouseout="changeImages(/*CMP*/ 'object', /*URL*/ 'images/indexhome.jpg'); return true;"><img
 512  src="images/indexhome.jpg" name="object" alt="Home" border="0"
 513  height="46" width="73"></a></td>
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