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 113 <div id="Layer1"
 114  style="position: absolute; left: 335px; top: 42px; width: 388px; height: 43px; z-index: 1; font-size: x-small;">
 115 <div class="style1" align="right">Download</div>
 116 </div>
 117 <div id="Layer2"
 118  style="position: absolute; left: 226px; width: 497px; z-index: 2; top: 188px; height: 877px;">
 119 <h3 class="heading1">Download</h3>
 120
 121 <p style="text-align: justify;">
 122
 123 PsN is distributed  as a gziped tar ball and zipped file. Both should work
 124 on both Windows and UNIX.</p>
 125
 126 <table style="width: 100%;" border="0" cellpadding="4" cellspacing="4">
 127   <tbody>
 128 <!--    <tr>
 129       <td>
 130       <p><a href="http://prdownloads.sourceforge.net/psn/PsN-2.1.10.tar.gz?download" target="_blank">PsN-2.1.10.tar.gz</a></p>
 131       </td>
 132       <td>
 133       <p>This is the latest development release.</p>
 134       </td>
 135       <td>
 136       <p>2005-10-14</p>
 137       </td>
 138     </tr>
 139     <tr>
 140       <td>
 141       <p><a href="http://prdownloads.sourceforge.net/psn/PsN-2.1.10.zip?download" target="_blank">PsN-2.1.10.zip</a></p>
 142       </td>
 143       <td>
 144       <p>This is the latest development release.</p>
 145       </td>
 146       <td>
 147       <p>2005-10-14</p>
 148       </td>
 149     </tr> -->
 150     <tr>
 151       <td colspan="3">
 152       <p><b>Latest stable release</b></p>      </td>
 153     </tr>
 154     <tr>
 155       <td colspan="3">
 156           <tr>
 157       <td><p><a href="http://prdownloads.sourceforge.net/psn/PsN-2.2.1.tar.gz?download" target="_blank">PsN-2.2.1.tar.gz</a></p></td>
 158       <td>Mostly bug fixes. See the README.txt for details.</td>
 159       <td><p>2006-11-07</p></td>
 160     </tr>
 161     <tr>
 162       <td><p><a href="http://prdownloads.sourceforge.net/psn/PsN-2.2.1.zip?download" target="_blank">PsN-2.2.1.zip</a></p></td>
 163       <td><p>&nbsp;</p></td>
 164       <td><p>2006-11-07</p></td>
 165     </tr>
 166     <tr>
 167       <td colspan="3">
 168       <p><b>Older releases</b></p></td>
 169     </tr>
 170     <tr>
 171       <td colspan="3">
 172           <tr>
 173       <td><p><a href="http://prdownloads.sourceforge.net/psn/PsN-2.2.0.tar.gz?download" target="_blank">PsN-2.2.0.tar.gz</a></p></td>
 174       <td><p>The new 2.2.0 release</p></td>
 175       <td><p>2006-08-09</p></td>
 176     </tr>
 177     <tr>
 178       <td><p><a href="http://prdownloads.sourceforge.net/psn/PsN-2.2.0.zip?download" target="_blank">PsN-2.2.0.zip</a></p></td>
 179       <td><p>&nbsp;</p></td>
 180       <td><p>2006-08-09</p></td>
 181     </tr>
 182     <tr>
 183       <td colspan="3" style="vertical-align: top;"><p>&nbsp;</p></td>
 184     </tr>
 185     <tr>
 186       <td colspan="3">
 187       <p><b>Beta releases</b></p></td>
 188     </tr>
 189     <tr>
 190       <td colspan="3">
 191           <tr>
 192         <td colspan="3" style="vertical-align: top;"><p>We have begun to release beta tests of the stable releases. In these we will include all bug fixes and feature additions  that we think are suitable to add quickly to the stable branch. </p></td>
 193       </tr>
 194           <tr>
 195       <td><p><a href="http://prdownloads.sourceforge.net/psn/PsN-2.2.2-beta1.tar.gz?download" target="_blank">PsN-2.2.2-beta1.tar.gz</a></p></td>
 196       <td><p>First beta of the 2.2.2 release. </p></td>
 197       <td><p>2006-11-08</p></td>
 198     </tr>
 199     <tr>
 200       <td><p><a href="http://prdownloads.sourceforge.net/psn/PsN-2.2.2-beta1.zip?download" target="_blank">PsN-2.2.2-beta1.zip</a></p></td>
 201       <td><p>&nbsp;</p></td>
 202       <td><p>2006-11-08</p></td>
 203     </tr>
 204     <tr>
 205       <td colspan="3" style="vertical-align: top;"><p>&nbsp;</p></td>
 206     </tr>
 207     <tr>
 208       <td colspan="3" style="vertical-align: top;"><p><b>PsN Development release</b></p></td>
 209     </tr>
 210     <tr>
 211       <td colspan="3" style="vertical-align: top;"><p>There is currently no development version available, but we are
 212           planning to implement some interresting features and a release
 213           of 2.3.0 might apear here then.</p></td>
 214     </tr>
 215   </tbody>
 216 </table>
 217
 218 <p>&nbsp;</p>
 219 <h3 class="heading1">Version numbers</h3>
 220
 221 <p style="text-align: justify;">
 222
 223 The PsN project follows the Linux style version numbering. The format
 224 is X.Y.Z where X is major version. The Y is minor version and
 225 increases when significant features are added or changed. The minor
 226 version is even for stable release, and odd for development
 227 releases. The Z is a revision number, it changes more often and
 228 signifies smaller changes, mostly bug fixes.<br> </p>
 229
 230 <p style="text-align: justify;">
 231
 232 Older PsN versions is available from the <a target="_blank"
 233 href="http://sourceforge.net/projects/psn/">SourceForge project
 234 page</a>. (Look under the <a
 235 href="http://sourceforge.net/project/showfiles.php?group_id=101419">files</a>
 236 section). The project page also explains how to access the SourceForge
 237 CVS, the repository where the latest changes to PsN are stored. However, if you
 238 download PsN from the CVS the stability is not guaranteed - it might
 239 be broken. </p>
 240
 241 <h3 class="heading1">Compatibility<br> </h3>
 242
 243 <p align="justify">PsN is tested with Perl 5.8.4 and 5.8.6 to 5.8.8 on
 244 Linux. On Windows its tested with <a target="_blank"
 245  href="http://www.activestate.com/Products/ActivePerl/">ActiveState</a>
 246 ActivePerl 5.6.8.811. To compile NONMEM <a target="_blank"
 247 href="http://www.gnu.org">GNU</a> G77 version 3.3.5 and Compaq's <a
 248 target="_blank" href="http://www.qtsoftware.de/dvf/">Digital Visual
 249 Fortran version 5.0</a> have been tested.
 250 <p>PsN development is done under Linux, therefore the function under
 251 Windows is less tested.
 252 <p align="justify">
 253
 254 One aim of PsN is to make it platform independent. So please do try
 255 PsN on other platforms and with other Perl versions and compilers and
 256 report your success or failure.
 257
 258 <h3 class="heading1">Installation instructions<br> </h3>
 259
 260 <p>Installation is easy and consists of five simple
 261 steps.</p>
 262
 263 <p style="font-weight: bold;">Installation using the provided setup
 264 script</p> <ol>
 265   <li>
 266     <p>Unpack the file you downloaded. It will create a directory
 267        called <tt>PsN-Source.</tt></p>
 268   </li>
 269   <li>
 270     <div style="text-align: justify;">
 271
 272     <p align="justify">Run the installation script from within <tt>PsN-Source</tt>.
 273        If you are running windows and have <a target="_blank"
 274  href="http://www.activestate.com/Products/ActivePerl/">ActiveState
 275       ActivePerl</a> installed you should be able to double click on
 276       <tt>setup.pl</tt>. Otherwise open a command line window, go to
 277       the <tt>PsN-Source </tt>directory and type: </p>
 278     </div>
 279     <p><tt>perl setup.pl</tt></p>
 280     <p>Unix users should open their favorite terminal go to the <tt>PsN-Source</tt> directory and type: </p>
 281     <p><tt>perl setup.pl</tt></p>
 282   </li>
 283   <li style="text-align: justify;">
 284
 285     <p>Answer the questions on screen. The default is probably the
 286        best for most users. If you cannot install PsN were the install
 287        script suggests and you wish to use PsN in your own perl
 288        scripts, you must make sure that the directory where you
 289        installed the PsN core and toolkit is in Perl's include
 290        path. For convenience You should also check that the directory
 291        where the utilities are installed is in your search path.
 292       </p>
 293
 294   </li>
 295   <li>
 296
 297     <p style="text-align: justify;">Edit the configuration file
 298     (<tt>PsN-installdir/PsN/psn.conf</tt>) to make PsN aware your NONMEM
 299     installation: </p> <p> For a more detailed documentation of the psn.conf <a href="psn_conf.php">look here.</a></p>
 300
 301     <p><span style="font-family: monospace;">[nm_versions]</span>
 302       <br style="font-family: monospace;">
 303       <span style="font-family: monospace;">5=/export/home/nmv1.1</span>
 304       <br style="font-family: monospace;">
 305       <span style="font-family: monospace;">5_big=/export/home/nmv1.1_big</span><br>
 306       <br style="font-family: monospace;">
 307       <span style="font-family: monospace;">[compiler]</span>
 308       <br style="font-family: monospace;">
 309       <span style="font-family: monospace;">; Gnu fortran compiler</span>
 310       <br style="font-family: monospace;">
 311       <span style="font-family: monospace;">name=g77</span>
 312       <br style="font-family: monospace;">
 313       <span style="font-family: monospace;">options=-W -static -O</span>
 314
 315     </p>
 316     <div style="text-align: justify;">
 317     <p>The header <tt>[nm_versions]</tt> must always be present. Each
 318 line under the <tt>nm_version</tt> header corresponds to a NONMEM version. To
 319 the left of the equal sign is a version identifier which is a number
 320 or a text that identifies an installation of NONMEM. This is the
 321 identifier you give to the PsN utilities using the option <tt>-nm_version</tt>.
 322 To the right is the directory where the version of NONMEM is installed.</p>
 323
 324     <p>The <tt>[compiler]</tt> section is optional but necessary if you have
 325 another compiler than g77. The <tt>compiler</tt> section has two
 326 lines. One starting with <tt>name</tt> on the left of the equal sign
 327 which is the compiler executable name. You should include a path if you
 328 don't have the compiler directory in you environment path. The second
 329 line is the <tt>options</tt> line where you specify compiler options,
 330 such as optimizations. (Note that
 331 lines starting with ; are ignored.)</p>
 332
 333     </div>
 334   </li>
 335   <li>When the installation is
 336         done you can safely remove the <tt>PsN-Source</tt>
 337     directory if you like.</li>
 338   </ol>
 339 <br>
 340 <p style="font-weight: bold;">Manual installation</p>
 341 <p></p>
 342
 343 <p><b> As of version 2.2 we strongly encourage use of the installation
 344 script, it is stable and should work fine for most people. Should it
 345 fail for you, or have problems with installing an older PsN version, please contact us.</b> </p>
 346 <!--
 347  <ol>
 348   <li>
 349     <p>Unpack the file you downloaded. It will create a directory
 350 called <tt>PsN-Source.</tt></p>
 351   </li>
 352   <li>
 353     <p align="justify">Copy the <tt>PsN-Source\lib</tt> to a directory which is in the
 354 Perl include path. Make sure you name the directory <tt>PsN</tt>. Then
 355 copy the contents of <tt>PsN-Source\bin</tt> to a place that is in
 356 your systems path.
 357
 358 On my Windows installation of Perl I place the <tt>PsN-Source\lib</tt>
 359 directory in <tt>C:\perl\site\lib</tt>. And the contents of
 360 <tt>PsN-Source\bin</tt> in <tt>C:\perl\bin</tt>.
 361
 362 <p align="justify"> To get the Windows command line to recognize that the programs you
 363 just copied to <tt>C:\perl\bin</tt> you must create a batch file for
 364 each program. The easiest way is to just copy the <tt>runperl.bat</tt>
 365 that comes with ActiveState's Perl distribution. Make one copy for each
 366 program with the same name as the program but with the <tt>.bat</tt>
 367 extension.
 368 <p align="justify">
 369 For example, on a Gentoo Linux installation of Perl a good spot to place the
 370 <tt>PsN-Source\lib</tt> directory is in
 371 <tt>/usr/lib/perl5/site_perl/5.8.5</tt> and the
 372 <tt>PsN-Source\bin</tt> contents in <tt>/usr/bin</tt>
 373
 374     </p>
 375   </li>
 376   <li>
 377     <p align="justify">Next you must copy <span style="font-family:
 378 monospace;">PsN.pm</span> from the <tt>PsN-Source\lib</tt> to the
 379 directory just above the <tt>PsN</tt> you just created. Then you must
 380 edit it to find the PsN directory. The file looks something like this.<p align="justify">
 381
 382
 383 <span style="font-family: monospace;">package PsN;</span>
 384 <br style="font-family: monospace;">
 385 <span style="font-family: monospace;">use lib 'c:\perl\site\lib\PsN';</span>
 386 <br style="font-family: monospace;">
 387 <span style="font-family: monospace;">$config_file = "c:\perl\site\lib\PsN\psn.conf';</span>
 388 <br style="font-family: monospace;">
 389 <span style="font-family: monospace;">1;</span>
 390 <p align="justify">
 391 Now change the paths to where you installed PsN.<br>
 392     </p>
 393   </li>
 394   <li>
 395     <p align="justify">Edit the configuration, in the same way as in automatic
 396 installation.</p>
 397   </li>
 398   <li>
 399     <p align="justify">Install extra packages. At the time of writing, they are:</p>
 400   </li>
 401   <div align="justify">
 402
 403      <ul>
 404          <li> <a target="_blank"
 405  href="http://search.cpan.org/%7Egrommel/Math-Random-0.67/">Math::Random-0.67</a></li>
 406          <li><a target="_blank"
 407  href="http://search.cpan.org/%7Eams/Storable-2.13/">Storable::Store-0.67</a> (included with ActiveState Perl for Windows.)
 408         </li>
 409       </ul>
 410        <p align="justify">All are available from <a target="_blank"
 411  href="http://www.cpan.org/">CPAN.</a></p>
 412       </li>
 413   </div>
 414   <div align="justify"><li>When the installation is done you can safely remove the <tt>PsN-Source</tt>
 415 directory if you like.</div>
 416     </li>
 417   </ol>
 418 -->
 419 <p>&nbsp;</p>
 420 </div>
 421 <table border="0" cellpadding="0" cellspacing="0" width="780">
 422   <tbody>
 423     <tr>
 424       <td height="600" width="780">
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 434  src="images/indexpane1_2_.jpg" name="" alt="" border="0" height="46"
 435  width="26"></td>
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 437  onmouseover="changeImages(/*CMP*/ 'object', /*URL*/ 'images/indexhomeov.jpg'); return true;"
 438  onmouseout="changeImages(/*CMP*/ 'object', /*URL*/ 'images/indexhome.jpg'); return true;"><img
 439  src="images/indexhome.jpg" name="object" alt="Home" border="0"
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 458             <td colspan="7" height="7" width="780"><img
 459  src="images/indexpane1_3_.jpg" name="" alt="" border="0" height="7"
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 463             <td height="46" width="26"><img
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 477  src="images/indexpane1_5_.jpg" name="" alt="" border="0" height="7"
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 488  src="images/indexdownload.jpg" name="object2" alt="Download" border="0"
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 495             <td colspan="7" height="7" width="780"><img
 496  src="images/indexpane1_7_.jpg" name="" alt="" border="0" height="7"
 497  width="780"></td>
 498           </tr>
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 501  src="images/indexpane1_8_.jpg" name="" alt="" border="0" height="46"
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