2 ; Available output styles are SPLUS, MATLAB and EXCEL
3 ; The only differences are:
5 ; missning_data 'NA' 'NaN' ''
6 ; Header row yes no yes
8 ; The default output style is EXCEL
10 ; These two lines should not be modified, they are used to disable
11 ; experimental features of PsN.
14 ; Further experimental features
15 ;database_server=localhost
19 ; The following lines are LSF options.
20 remote_perl=some_path_to_a_perl_binary_working_on_remote_hosts
22 ; The following lines are nordugrid options
23 ; ng_clusters=some_path_to_a_file_with_cluster_names
25 ; The lines below are examples of how you can specify different
26 ; installations of NONMEM. By default, PsN will use the NONMEM
27 ; installation identified by the name 'default'. If only one
28 ; installation is specified, this will be used by default even if it
29 ; isn't called 'default'. To use other installations with the
30 ; PsN-utilities scripts, use the "-nm_version" command line
31 ; option. The last line is an example of how a windows installation
32 ; could be configured (notice the use of a backslash(\) instead of a
40 ; The compiler section specifies the name and compiler flags of the
41 ; compiler executable. It is also possible to include a path. Like
43 ; name=c:\fortran\fl32
46 ; Gnu fortran compiler
51 ;;MS Fortran Powerstation
56 ;;Digitial Visual Fortran 5.0
58 ;options=/optimize:4 /fltconsistency /fpe:3
59 ;;options=/optimize:1 /fpe:0
67 ; Options valid for all tools
71 [default_execute_options]
72 ; Options valid for execute
74 ; All correlations above this number will be listed
77 ; An error will be rised if the condition number is greater than this
80 condition_number_limit = 1000
82 ; If a parameter estimate is equal to a bound with this many
83 ; significant digits, a warning will be printed.
85 near_bound_sign_digits = 2
87 ; When the bound is zero, the check above is not valid. Use this limit
90 near_zero_boundary_limit = 0.001
92 ; The off-diagonal elements are checked against +-1 with this many
95 sign_digits_off_diagonals = 2
97 ; Coefficients of variation larger than these numbers will produce
100 large_theta_cv_limit = 0.30
101 large_omega_cv_limit = 0.50
102 large_sigma_cv_limit = 0.30
104 ; Confidence level for confidence intervals (percentage value)
106 confidence_level = 95
108 ; Precision in -summarize output.
112 [default_llp_options]
113 ; Options valid for llp
115 ; Check if the confidence intervals include this value
116 within_interval_check = 0
118 ; Check if the CI limit distance ratio is above this value or below its reciprocal value
119 theta_interval_ratio_check = 1.3
120 omega_interval_ratio_check = 1.6
121 sigma_interval_ratio_check = 1.6
123 [default_cdd_options]
124 ; Options valid for cdd
126 ; Mark the cook-scores and covariance-ratios that lie outside this number of standard deviations
127 outside_n_sd_check = 2
129 [default_bootstrap_options]
130 ; Options valid for the bootstrap
132 ; Use these rules for calculating the bootstrap results
133 skip_minimization_terminated = 1
134 skip_covariance_step_terminated = 0
135 skip_with_covstep_warnings = 0
136 skip_estimate_near_boundary = 1
138 ; Warn if the ratio of successful minimizations/total runs is lower than this value
139 minimization_successful_limit = 0.8
141 ; Warn if the ratio of successful covariance steps/total runs is lower than this value
142 covariance_step_successful_limit = 0.8
144 ; Warn if the ratio of runs with covariance step warnings/total runs is higher than this value
145 covariance_step_warnings_limit = 0.2
147 ; Warn if the ratio of runs with near boundary warnings/total runs is higher than this value
148 estimate_near_boundary_limit = 0.2
150 ; Warn if the ratio of runs with near boundary warnings/total runs is higher than this value
151 estimate_near_boundary_limit = 0.2
153 ; Use this level of confidence for the confidence intervals checks based on bootstrap standerd errors (%)
154 se_confidence_intervals_level = 5
156 ; Use this level of confidence for the confidence intervals checks based on bootstrap percentiles (%)
157 percentile_confidence_intervals_level = 5
159 ; Use this level of confidence for the confidence intervals checks based on bootstrap BCa percentiles (%)
160 bca_confidence_intervals_level = 5
162 ; Check if the confidence intervals based on bootstrap standerd errors include this value
163 se_confidence_intervals_check = 0
165 ; Check if the confidence intervals based on bootstrap percentiles include this value
166 percentile_confidence_intervals_check = 0
168 ; Check if the confidence intervals based on bootstrap BCa percentiles include this value
169 bca_confidence_intervals_check = 0
171 ; Warn if the absolute relative bias is larger than this value
172 large_bias_limit = 0.05