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1 1 METABOLISM
2 1.01 amino-acid metabolism
3 1.01.01 amino-acid biosynthesis
4 1.01.04 regulation of amino-acid metabolism
5 1.01.10 amino-acid degradation (catabolism)
6 1.01.99 other amino-acid metabolism activities
7 1.02 nitrogen and sulphur metabolism
8 1.02.01 nitrogen and sulphur utilization
9 1.02.04 regulation of nitrogen and sulphur utilization
10 1.02.99 other nitrogen and sulphur metabolism activities
11 1.03 nucleotide metabolism
12 1.03.01 purine-ribonucleotide metabolism
13 1.03.04 pyrimidine-ribonucleotide metabolism
14 1.03.07 deoxyribonucleotide metabolism
15 1.03.10 metabolism of cyclic and unusual nucleotides
16 1.03.13 regulation of nucleotide metabolism
17 1.03.16 polynucleotide degradation
18 1.03.16.01 RNA degradation
19 1.03.19 nucleotide transport
20 1.03.99 other nucleotide-metabolism activities
21 1.04 phosphate metabolism
22 1.04.01 phosphate utilization
23 1.04.04 regulation of phosphate utilization
24 1.04.07 phosphate transport
25 1.04.99 other phosphate metabolism activities
26 1.05 C-compound and carbohydrate metabolism
27 1.05.01 C-compound and carbohydrate utilization
28 1.05.01.01 C-compound, carbohydrate catabolism
29 1.05.01.01.01 sugar, glucoside, polyol and carboxylate catabolism
30 1.05.01.01.03 C-2 compound, organic acid and fatty acid catabolism
31 1.05.01.03 C-compound, carbohydrate anabolism
32 1.05.01.03.02 polysaccharide biosynthesis
33 1.05.01.03.04 aminosaccharide biosynthesis
34 1.05.01.05 autotrophic CO2-fixation
35 1.05.04 regulation of C-compound and carbohydrate utilization
36 1.05.07 C-compound, carbohydrate transport
37 1.05.99 other carbohydrate metabolism activities
38 1.06 lipid, fatty-acid and isoprenoid metabolism
39 1.06.01 lipid, fatty-acid and isoprenoid biosynthesis
40 1.06.01.01 phospholipid biosynthesis
41 1.06.01.05 fatty acid biosynthesis
42 1.06.01.07 isoprenoid biosynthesis
43 1.06.01.07.11 tetracyclic and pentacyclic triterpenes (steroids and hopanoids) biosynthesis
44 1.06.04 breakdown of lipids, fatty acids and isoprenoids
45 1.06.07 lipid, fatty-acid and isoprenoid utilization
46 1.06.10 regulation of lipid, fatty-acid and isoprenoid biosynthesis
47 1.06.13 lipid and fatty-acid transport
48 1.06.99 other lipid, fatty-acid and isoprenoid metabolism activities
49 1.07 metabolism of vitamins, cofactors, and prosthetic groups
50 1.07.01 biosynthesis of vitamins, cofactors, and prosthetic groups
51 1.07.04 utilization of vitamins, cofactors, and prosthetic groups
52 1.20 secondary metabolism
53 1.20.01 metabolism of primary metabolic sugars derivatives
54 1.20.01.01 biosynthesis of secondary monosaccharides
55 1.20.01.07 biosynthesis of glycosides
56 1.20.13 biosynthesis of derivatives of homoisopentenyl pyrophosphate
57 1.20.15 biosynthesis of derivatives of dehydroquinic acid, shikimic acid and chorismic acid
58 1.20.17 biosynthesis of secondary products derived from primary amino acids
59 1.20.35.01 biosynthesis of stilbenes, flavonoids
60 1.20.37 biosynthesis of peptide derived compounds
61 1.20.99 other secondary metabolism activities
63 2 ENERGY
64 2.01 glycolysis and gluconeogenesis
65 2.07 pentose-phosphate pathway
66 2.07.01 pentose-phosphate pathway oxidative branch
67 2.10 tricarboxylic-acid pathway
68 2.11 electron transport and membrane-associated energy conservation
69 2.11.01 electron transport proteins
70 2.11.03 ATP synthesis proteins
71 2.11.05 accessory proteins of electron transport and membrane-associated energy conservation
72 2.11.99 other electron transport and membrane-associated energy conservation proteins
73 2.13 respiration
74 2.13.01 anaerobic respiration
75 2.13.05 aerobic respiration
76 2.16 fermentation
77 2.16.01 alcohol fermentation
78 2.19 metabolism of energy reserves (glycogen, trehalose)
79 2.22 glyoxylate cycle
80 2.25 oxidation of fatty acids
81 2.30 photosynthesis
82 2.30.01electron transport proteins of photosynthesis
83 2.30.03 accessory proteins of photosynthetic electron transport
84 2.99 other energy generation activities
86 3 CELL GROWTH, CELL DIVISION AND DNA SYNTHESIS
87 3.13 meiosis
88 3.16 DNA synthesis and replication
89 3.19 recombination and DNA repair
90 3.99 other cell growth, cell division and DNA synthesis activities
92 4 TRANSCRIPTION
93 4.01 rRNA transcription
94 4.01.01 rRNA synthesis
95 4.01.04 rRNA processing
96 4.01.99 other rRNA-transcription activities
97 4.03 tRNA transcription
98 4.03.01 tRNA synthesis
99 4.03.03 tRNA processing
100 4.03.06 tRNA modification
101 4.03.99 other tRNA-transcription activities
102 4.05 mRNA transcription
103 4.05.01 mRNA synthesis
104 4.05.01.01 general transcription activities
105 4.05.01.04 transcriptional control
106 4.05.03 mRNA processing (splicing)
107 4.05.05 mRNA processing (5'-, 3'-end processing, mRNA degradation)
108 4.05.99 other mRNA-transcription activities
109 4.99 other transcription activities
111 5 PROTEIN SYNTHESIS
112 5.01 ribosomal proteins
113 5.04 translation
114 5.07 translational control
115 5.10 tRNA-synthetases
116 5.99 other protein-synthesis activities
118 6 PROTEIN DESTINATION
119 6.01 protein folding and stabilization
120 6.04 protein targeting, sorting and translocation 6.07
121 6.07 protein modification
122 6.10 assembly of protein complexes
123 6.13 proteolysis
124 6.13.01 cytoplasmic and nuclear degradation
125 6.13.04 lysosomal and vacuolar degradation
126 6.13.07 other proteolytic degradation
127 6.99 other protein-destination activities
129 7 TRANSPORT FACILITATION
130 7.01 channels/pores
131 7.04 ion transporters
132 7.04.01 metal ion transporters (Cu, Fe, etc.)
133 7.04.03 other cation transporters (Na, K, Ca , NH4, etc.)
134 7.04.99 anion transporters (Cl, SO4, PO4, etc.)
135 7.07 C-compound and carbohydrate transporters
136 7.22 transport ATPases
137 7.25 ABC transporters
138 7.99 other transport facilitators
140 8 CELLULAR TRANSPORT AND TRANSPORT MECHANISMS
141 8.01 nuclear transport
142 8.02 chloroplast transport
143 8.04 mitochondrial transport
144 8.07 vesicular transport (Golgi network, etc.)
145 8.10 peroxisomal transport
146 8.13 vacuolar transport
147 8.16 extracellular transport (secretion)
148 8.19 cellular import
149 8.22 cytoskeleton-dependent transport
150 8.99 other intracellular-transport activities
152 9 CELLULAR BIOGENESIS (proteins are not localized to the corresponding organelle)
153 9.01 biogenesis of cell wall (cell envelope)
154 9.03 biogenesis of plasma membrane
155 9.04 biogenesis of cytoskeleton
156 9.99 chloroplast biogenesis
158 10 CELLULAR COMMUNICATION/SIGNAL TRANSDUCTION
159 10.01 intracellular communication
160 10.03 unspecified signal transduction
161 10.05 receptor proteins
162 10.99 other unspecified signal transduction activities
164 11 CELL RESCUE, DEFENSE, CELL DEATH AND AGEING
165 11.01 stress response
166 11.03DNA repair
167 11.03.01nucleotide excision repair
168 11.05 Disease, virulence and defense
169 11.05.01 resistance proteins
170 11.05.03 defense related proteins
171 11.05.05 virulence, disease factors
172 11.05.05.99 other virulence, disease factors
173 11.05.99 other disease and defense related proteins
174 11.07 detoxificaton
175 11.07.01 detoxification involving cytochrome P450
176 11.07.03 detoxification by modification
177 11.07.99 other detoxification
178 11.10 cell death and ageing
179 11.10.09 degradation of exogenous ester compounds
180 11.99 other cell rescue activities
182 13 IONIC HOMEOSTASIS
183 13.04 ionic homeostasis
185 30 CELLULAR ORGANIZATION (proteins are localized to the corresponding organelle)
186 30.01 organization of cell wall
187 30.02 organization of plasma membrane
188 30.03 organization of cytoplasm
189 30.04 organization of cytoskeleton
190 30.07 organization of endoplasmatic reticulum
191 30.08 organization of Golgi
192 30.09 organization of intracellular transport vesicles
193 30.10 nuclear organization
194 30.13 organization of chromosome structure
195 30.16 mitochondrial organization
196 30.19 peroxisomal organization
197 30.25 vacuolar and lysosomal organization
198 30.26 chloroplast organization
199 30.99 other cellular organization
201 98 CLASSIFICATION NOT YET CLEAR-CUT
203 99 UNCLASSIFIED PROTEINS