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[sgn.git] / cgi-bin / community / feature / 200410.pl
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1 use strict;
2 use CXGN::Page;
3 my $page=CXGN::Page->new('200410.html','html2pl converter');
4 my $stylesheet=<<END_STYLESHEET;
5 <style type="text/css">
6 <!--
7 body {
8 color: #000000;
9 background-color: #ffffff;
12 p {
13 margin-left: 40px;
14 text-align: justify;
17 .footnote {
18 font-size: small;
19 /*width: 700px;*/
20 text-align:center;
23 .bibliography {
24 text-indent: -20px;
26 -->
27 </style>
28 END_STYLESHEET
29 $page->header('The Botella Lab', undef, $stylesheet);
30 print<<END_HEREDOC;
32 <center>
33 <h1>The Botella Lab</h1>
34 </center>
36 <p class="footnote"><img src="/static_content/community/feature/200410.jpg" border="0" width="579"
37 height="384" alt="The Botella Lab" /><br />
38 From left to right: Upper row: David Pos&eacute;, Maria
39 Jos&eacute;, Itziar Castanedo, Karen Merchante, Ver&oacute;nica
40 Gonz&acute;lez, Sonia Osorio Lower row: Victoriano Valpuesta,
41 Eduardo Gross, Miguel A. Botella, Eduardo Cruz, Irene Araguez,
42 Abel Rosado, Aureliano Bombarely</p>
44 <h2>Research Interests</h2>
46 <p>Only a reduced number of genes have been identified as
47 critical for plant salt and drought tolerance. Using a genetic
48 approach we have identified several tomato mutants (tss)
49 hypersensitive to NaCl as well as 1 tomato (tos1) mutant
50 specifically hypersensitive to drought stress. In our laboratory
51 we use a combination of physiology, electrophysiology and
52 molecular techniques in the characterization of these tomato
53 mutants in order to define genes and processes important for salt
54 and drought tolerance in plants. We are in the process of cloning
55 some of these genes.</p>
57 <p>We are also using Arabidopsis in the identification of
58 additional genes that are essential for salt and drought stress.
59 In collaboration with Dr. Hasegawa we have identified a number of
60 T-DNA mutants that are hypersensitive to salt and osmotic stress.
61 We have identified the genes affected and we are working in the
62 characterization of these mutants. We work together with Dr.
63 Victoriano Valpuesta and his group and we are also interested in
64 fruit ripening in tomato and strawberry using genomic approaches.
65 We have identified an alternative pathway for vitamin C
66 biosynthesis in strawberry fruits. In this pathway, the
67 biosynthesis of vitamin C in ripe strawberry fruits, which are
68 rich in this compound, occurs through D-galacturonic acid, the
69 main constituent of cell-wall pectins. We have cloned a key gene
70 of this pathway, GalUR, encoding a protein with NADPH-dependent
71 D-galacturonate reductase activity that is specifically expressed
72 in ripe strawberry fruits. We are interested in determine how
73 universal is this pathway in other species including tomato.</p>
75 <p>Dr. Botella is Professor of the University of M&aacute;laga
76 (Spain) since 1999 and one of the directors of the Laboratorio de
77 Biotecnolog&iacute;a de Plantas (Plant Biotechnology Laboratory)
78 together with <a href="mailto:Valpuesta\@uma.es">Dr. Valpuesta</a>. He
79 obtained his Ph.D. at the University of M&aacute;laga in 1994
80 spending some periods during his doctorate at Purdue University.
81 After his Thesis, Dr. Botella worked as a posdoct in Purdue
82 University under the supervision of Dr. Paul M. Hasegawa with the
83 main focus on cysteine proteinase inhibitors. Later he spent 4
84 years in the Sainsbury Laboratory (John Innes Centre) under the
85 supervision of Dr. Jonathan D.G. Jones working on Arabidopsis
86 Resistant Genes.</p>
88 <h2>Contact Information</h2>
90 <p>University of Malaga<br />
91 Dep. Biolog&iacute;a Molecular y Bioqu&iacute;mica<br />
92 Facultad de Ciencias<br />
93 Campus de Teatinos s/n<br />
94 29071 M&aacute;laga<br />
95 Spain</p>
97 <h2>Selected Publications</h2>
99 <p class="bibliography">Borsani O, Valpuesta V, Botella MA (2001)
100 Evidence for a role of salicylic acid in the oxidative damage
101 generated by NaCl and osmotic stress in Arabidopsis seedlings.
102 Plant Physiol 126: 1024-1030</p>
104 <p class="bibliography">Borsani O, Cuartero J, Fernandez JA,
105 Valpuesta V, Botella MA (2001) Identification of two loci in
106 tomato reveals distinct mechanisms for salt tolerance. Plant Cell
107 13: 873-887</p>
109 <p class="bibliography">Borsani O, Cuartero J, Valpuesta V,
110 Botella MA (2002) Tomato tos1 mutation identifies a gene
111 essential for osmotic tolerance and abscisic acid sensitivity.
112 Plant Journal 32: 905-914</p>
114 <p class="bibliography">Gonzalez-Lamothe R, Segura R, Trapero A,
115 Baldoni L, Botella MA, Valpuesta V (2002) Phylogeny of the fungus
116 Spilocaea oleagina, the causal agent of peacock leaf spot in
117 olive. FEMS Microbiology Lett 210: 149-155</p>
119 <p class="bibliography">Borsani, O., Valpuesta, V., and Botella,
120 M.A. Developing salt tolerance plants in a new century: a
121 molecular biology approach (Review). Plant Cell Tissue and Organ
122 Culture 73: 101-115</p>
124 <p class="bibliography">Agius F, Gonzalez-Lamothe R, Caballero
125 JL, Munoz-Blanco J, Botella MA, Valpuesta V (2003) Engineering
126 increased vitamin C levels in plants by overexpression of a
127 D-galacturonic acid reductase. Nature Biotechnology 21:
128 177-181</p>
130 <p class="bibliography">Rubio L, Rosado A, Linares-Rueda A,
131 Borsani O, Garc&iacute;a-S&aacute;nchez MJ, Valpuesta V,
132 Fern\341ndez JA, Botella MA. (2004) Regulation of K+ Transport in
133 Tomato Roots by the TSS1 Locus. Implications in Salt Tolerance.
134 Plant Physiology 134: 452-459</p>
136 <p class="bibliography">Castillejo C, Delafuente JI, Iannetta P,
137 Botella MA and Victoriano Valpuesta. (2004). Pectin esterase gene
138 family in strawberry fruit. Study of FaPE1, a ripening-specific
139 isoform. Journal Experimental Botany. 55: 909-918.</p>
141 <p class="bibliography">Valpuesta V, Botella MA. (2004)
142 Biosynthesis of L-ascorbic acid in plants: New pathways for an
143 old antioxidant. Trends in Plant Science. In press.</p>
145 <p class="bibliography">Agius F, Amaya I, Botella MA, Valpuesta
146 V. (2004) Functional analysis of homologous and heterologous
147 promoters in strawberry fruits using transient expression.
148 Journal Experimental Botany. In press.</p>
149 END_HEREDOC
150 $page->footer();